Miyahira Mateus Kenji Christo, Novaretti João Victor, Astur Diego Costa, Kaleka Camila Cohen, Amaro Joicemar Tarouco, Cohen Moisés
Instuto Cohen de Ortopedia, Reabilitação e Medicina do Esporte, São Paulo, SP, Brasil.
Departamento de Ortopedia e Traumatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brasil.
Rev Bras Ortop (Sao Paulo). 2021 Jun;56(3):333-339. doi: 10.1055/s-0040-1712493. Epub 2020 Sep 25.
To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical evaluation was made by comparing the Lysholm and International Knee Document Commitee (IKDC) scores in the pre- and postoperative period of 12 months, and radiological evaluation using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score in the same postoperative period. The mean age of the patients was 39.2 years old, and the mean size of the chondral lesions was 1.55cm . There was a significant improvement in clinical scores, with a mean increase of 24.6 points on Lysholm and of 24.3 on IKDC after 12 months. In the radiological evaluation, MOCART had a mean of 65 points. It was observed that the larger the size of the lesion, the greater the improvement in scores. Evaluating subjective clinical scores, the treatment of chondral lesions with the collagen membrane showed good results, as well as the evaluation of MOCART, with greater benefit in larger lesions.
临床和影像学评估使用胶原膜-自体基质诱导软骨形成（AMIC）治疗软骨损伤的结果。 这是一系列观察性病例，分析了15例行AMIC治疗的患者。通过比较12个月术前和术后的Lysholm评分和国际膝关节文献委员会（IKDC）评分进行临床评估，并在同一术后时期使用软骨修复组织磁共振观察（MOCART）评分进行影像学评估。 患者的平均年龄为39.2岁，软骨损伤的平均大小为1.55平方厘米。临床评分有显著改善，12个月后Lysholm评分平均增加24.6分，IKDC评分平均增加24.3分。在影像学评估中，MOCART平均得分为65分。观察到损伤面积越大，评分改善越大。 通过主观临床评分评估，用胶原膜治疗软骨损伤显示出良好的效果，MOCART评估也是如此，对较大损伤的益处更大。
