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异种抗淋巴细胞血清对初次免疫反应的抑制作用。

Suppression of primary immune response by heterologous anti-lymphocyte sera.

作者信息

Reuben C, Sundaram K, Phondke G P

出版信息

Immunology. 1978 Feb;34(2):223-30.

PMID:342399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1457684/
Abstract

The effect of anti-lymphocyte serum (ALS) on the primary immune response to sheep erythrocytes (SRBC) in rats was studied by the Jerne Plaque technique. ALS against normal rat lymph node cells, ALS(N) suppressed the immune response to SRBC when administered before the antigen and had no effect on the immune response when administered either with or after the antigen. ALS(I), which was produced against lymph node cells from SRBC immunized rats, produced significant immunosuppression when administered either before or after the antigen.

摘要

采用耶尔恩斑技术研究了抗淋巴细胞血清（ALS）对大鼠针对绵羊红细胞（SRBC）的初次免疫反应的影响。针对正常大鼠淋巴结细胞的抗淋巴细胞血清ALS（N），在抗原注射前给药时可抑制对SRBC的免疫反应，而在与抗原同时给药或在抗原注射后给药时对免疫反应无影响。针对经SRBC免疫的大鼠淋巴结细胞产生的抗淋巴细胞血清ALS（I），在抗原注射前或注射后给药时均产生显著的免疫抑制作用。

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引用本文的文献

1
Specific suppression of delayed hypersensitivity response to sheep erythrocytes by heterologous anti-lymphocyte serum.异种抗淋巴细胞血清对绵羊红细胞迟发型超敏反应的特异性抑制
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2
Suppression of secondary immune response by antilymphocyte serum: time relationship between immunization and administration of antilymphocyte serum.抗淋巴细胞血清对二次免疫反应的抑制作用：免疫接种与抗淋巴细胞血清给药之间的时间关系。
Immunology. 1979 Jan;36(1):159-64.

本文引用的文献

1
Adult Thymectomy: Effect on Recovery from Immunologic Depression in Mice.成人胸腺切除术：对小鼠免疫抑制恢复的影响。
Science. 1965 Jul 23;149(3682):432-5. doi: 10.1126/science.149.3682.432.
2
EFFECT OF LYMPHOCYTE DEPLETION BY THORACIC DUCT FISTULA AND ADMINISTRATION OF ANTILYMPHOCYTIC SERUM ON THE SURVIVAL OF SKIN HOMOGRAFTS IN RATS.胸导管瘘致淋巴细胞耗竭及给予抗淋巴细胞血清对大鼠皮肤同种移植存活的影响
Nature. 1963 Nov 16;200:702. doi: 10.1038/200702a0.
3
Time-dependent immunosuppressive effects of anti-thymocyte serum.抗胸腺细胞血清的时间依赖性免疫抑制作用。
Nature. 1967 Sep 30;215(5109):1481-2. doi: 10.1038/2151481a0.
4
Cell to cell interaction in the immune response. II. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes.免疫反应中的细胞间相互作用。II. 给受照射小鼠输注骨髓、胸腺或胸导管淋巴细胞后溶血素形成细胞的来源。
J Exp Med. 1968 Oct 1;128(4):821-37. doi: 10.1084/jem.128.4.821.
5
Differential effect of heterologous anti-lymphocyte serum on antibody-producing cells and antigen-sensitive cells.异种抗淋巴细胞血清对抗体产生细胞和抗原敏感细胞的不同作用。
J Immunol. 1968 Aug;101(2):325-32.
6
Quantitative in vitro titration of anti-lymphocyte serum.抗淋巴细胞血清的体外定量滴定
Indian J Exp Biol. 1970 Oct;8(4):329-30.
7
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Proc Natl Acad Sci U S A. 1966 Oct;56(4):1130-7. doi: 10.1073/pnas.56.4.1130.
9
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Eur J Immunol. 1971 Dec;1(6):478-82. doi: 10.1002/eji.1830010614.
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J Immunol. 1971 Dec;107(6):1706-13.

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