Müller R D, Czeglarski G, Bamberg M, Budach V
Strahlenklinik des Universitätsklinikums Essen.
Strahlenther Onkol. 1987 Dec;163(12):755-63.
173 patients suffering from prostate carcinomas of stages A to C received percutaneous irradiations. The five-year survival is 100% in stage A (n = 6), 79% in stage B (n = 41), and 68% in stage C (n = 126). 116 patients received only percutaneous irradiation after needle biopsy, 30 patients were irradiated subsequently to surgical intervention, and 27 were treated by hormones during primary therapy. An analysis was made about survival, recurrence rate, metastasis-free interval, and incidence of metastases in dependence on stage, grading, and different forms of primary treatment. The importance of stage and grading as prognostic factors is confirmed by the results of this study. Extended primary therapy (surgery and/or hormones) seems to bring no benefit as compared to radiotherapy alone. Transurethral resection of the prostate as a surgical/diagnostic intervention has an unfavorable influence on the prognosis.
173例A至C期前列腺癌患者接受了经皮照射。A期(n = 6)患者的五年生存率为100%,B期(n = 41)为79%,C期(n = 126)为68%。116例患者在穿刺活检后仅接受经皮照射,30例患者在手术干预后接受照射,27例患者在初始治疗期间接受激素治疗。对生存、复发率、无转移间期以及转移发生率进行了分析,分析依据分期、分级和不同形式的初始治疗。本研究结果证实了分期和分级作为预后因素的重要性。与单纯放疗相比,扩大的初始治疗(手术和/或激素治疗)似乎并无益处。经尿道前列腺切除术作为一种手术/诊断干预措施对预后有不利影响。