Zanoni Sophia, Watts Brennan P, Tvrdy Kevin
Department of Chemistry & Biochemistry, University of Colorado, Colorado Springs, Colorado Springs, Colorado 80918, United States.
ACS Appl Mater Interfaces. 2021 Jul 21;13(28):33635-33643. doi: 10.1021/acsami.1c06961. Epub 2021 Jul 9.
Despite the commercial availability of many different hydrogel formulations, the effective gel-based purification of single-walled carbon nanotubes (SWNT) remains exclusive to the gel Sephacryl S-200. In this study, 12 commercially available gels and two custom-synthesized gels were investigated for their ability to effectively purify SWNT, as determined through quantification of SWNT adsorption, elution, chiral selectivity, and overall process efficiency. The ability of each gel to separate SWNT was found to correlate with physiochemical properties, such as hydrogel pore size, the presence of ionic ligands, and both polysaccharide backbone and cross-linker compositions. While Sephacryl S-200 demonstrated superior separation efficiency and chiral selectivity among the gels studied, Superose 6 was found to adsorb more SWNT than Sephacryl S-200 per cm of the gel surface area and exhibited a unique preference for the () and () SWNT chiralities, in contrast to the established selectivity of Sephacryl S-200 for the () chirality. Collectively, this work both identifies gels that exhibit unique SWNT chiral selectivity and provides insights into the rational design of gels tailored for SWNT purification.
尽管市面上有许多不同的水凝胶配方，但基于凝胶的单壁碳纳米管（SWNT）有效纯化方法仍仅适用于Sephacryl S - 200凝胶。在本研究中，通过对SWNT的吸附、洗脱、手性选择性和整体过程效率进行量化，研究了12种市售凝胶和两种定制合成凝胶有效纯化SWNT的能力。发现每种凝胶分离SWNT的能力与物理化学性质相关，如水凝胶孔径、离子配体的存在以及多糖主链和交联剂组成。虽然Sephacryl S - 200在研究的凝胶中表现出卓越的分离效率和手性选择性，但发现Superose 6每平方厘米凝胶表面积吸附的SWNT比Sephacryl S - 200更多，并且与Sephacryl S - 200对（）手性的既定选择性相反，对（）和（）SWNT手性表现出独特的偏好。总体而言，这项工作既确定了表现出独特SWNT手性选择性的凝胶，也为定制用于SWNT纯化的凝胶的合理设计提供了见解。
