Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
J Int Soc Sports Nutr. 2021 Jul 9;18(1):55. doi: 10.1186/s12970-021-00450-4.
Nitrate supplementation is thought to improve performance in endurance sports.
To meta-analyze studies evaluating the effect of nitrate supplementation on endurance sports performance among adults.
We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, Web of Science and CINAHL without language restrictions.
We included studies that: 1) compared nitrate supplementation with placebo; 2) enrolled adults engaging in an endurance-based activity; and 3) reported a performance measure or surrogate physiologic outcome. We evaluated risk of bias using the Cochrane Collaboration tool and pooled data with a random-effects model. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to evaluate confidence in estimates.
We included 73 studies (n = 1061). Nitrate supplementation improved power output (MD 4.6 watts, P < 0.0001), time to exhaustion (MD 25.3 s, P < 0.00001), and distance travelled (MD 163.7 m, P = 0.03). We found no significant difference on perceived exertion, time trial performance and work done. Nitrate supplementation decreased VO (MD - 0.04 L/min, P < 0.00001) but had no significant effect on VO or blood lactate levels.
The available evidence suggests that dietary nitrate supplementation benefits performance-related outcomes for endurance sports.
人们认为硝酸盐补充剂可以提高耐力运动的表现。
对评估硝酸盐补充剂对成年人耐力运动表现影响的研究进行荟萃分析。
我们在没有语言限制的情况下，检索了 Cochrane 中央对照试验注册库 (CENTRAL)、MEDLINE、EMBASE、Web of Science 和 CINAHL。
我们纳入了比较硝酸盐补充剂与安慰剂、招募进行基于耐力活动的成年人、并报告表现测量或替代生理结果的研究。我们使用 Cochrane 协作工具评估偏倚风险，并使用随机效应模型汇总数据。我们使用推荐评估、制定与评估 (GRADE) 方法来评估估计的置信度。
我们纳入了 73 项研究（n = 1061）。硝酸盐补充剂提高了功率输出（MD 4.6 瓦，P < 0.0001）、力竭时间（MD 25.3 秒，P < 0.00001）和行驶距离（MD 163.7 米，P = 0.03）。我们发现感知用力、计时赛表现和做功没有显著差异。硝酸盐补充剂降低了 VO（MD - 0.04 升/分钟，P < 0.00001），但对 VO 或血乳酸水平没有显著影响。
现有证据表明，饮食硝酸盐补充剂有益于耐力运动的表现相关结果。
Zotero 插件
