German Center for Integration and Migration Research (DeZIM), Mauerstr. 76, 10117 Berlin, Germany; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Psychology, 10117 Berlin, Germany.
Development, Health and Disease Research Program, University of California, 837 Health Sciences Drive, Irvine, CA 92697, United States.
Psychoneuroendocrinology. 2021 Oct;132:105349. doi: 10.1016/j.psyneuen.2021.105349. Epub 2021 Jul 1.
The association of acculturation with health among immigrant populations is believed to be mediated, in part, by acculturation-related stress and stress biology.
To review and qualitatively synthesize empirical findings on the relationship of acculturation with stress-related inflammatory and endocrine biomarkers and composite allostatic load (AL) scores.
A literature search was performed in the PubMed and PsycInfo databases. Article titles, abstracts or full-texts were screened and checked for match with the search criteria. Studies were eligible if they empirically tested the relationship between acculturation and inflammatory/endocrine stress biomarkers or composite AL scores, and were published in the English language.
Among the 41 articles identified as relevant and included in this review, the majority were published after 2010, included adult Hispanic U.S.-based populations, used cross-sectional study designs, operationalized acculturation as a unidimensional construct, and varied considerably in the selection of covariates in the analyses. Acculturation was significantly associated with stress biomarkers in 29 studies, but the direction of effects varied across studies. Specifically, acculturation, operationalized as a higher orientation towards the host culture, was associated with inflammatory biomarkers in 10 of 14 studies, with endocrine stress biomarkers in 12 of 20 studies, and with composite AL scores in 7 of 8 studies. Overall, language-based proxy measures of acculturation were related to higher levels of stress-related inflammatory and endocrine biomarkers and to lower levels of AL scores, whereas nativity-, generation status- and length of stay-based proxy measures of acculturation were related to higher levels of inflammatory biomarkers and AL score.
The majority of studies reported associations between measures of acculturation and stress biomarkers, however the directions of effects varied across studies. We suggest this heterogeneity may, in part, be a function of limitations imposed by cross-sectional research designs and unidimensional measures of acculturation measures, and we highlight the need for longitudinal studies and use of multidimensional measures of acculturation to better uncover the biobehavioral mechanisms and pathways linking acculturation with health outcomes.
人们认为，文化适应与移民群体的健康之间存在关联，这种关联部分是通过与文化适应相关的压力和压力生物学来介导的。
综述并定性综合实证研究结果，探讨文化适应与应激相关炎症和内分泌生物标志物及综合应激负荷（AL）评分之间的关系。
在 PubMed 和 PsycInfo 数据库中进行文献检索。筛选文章标题、摘要或全文，并检查其与搜索标准的匹配度。如果研究实证检验了文化适应与炎症/内分泌应激生物标志物或综合 AL 评分之间的关系，且以英文发表，则将其纳入本综述。
在确定的 41 篇相关文章中，大多数发表于 2010 年后，纳入了以美国成年西班牙裔人群为研究对象的研究，采用横断面研究设计，将文化适应定义为单维结构，在分析中纳入的协变量选择差异较大。29 项研究表明文化适应与应激生物标志物显著相关，但效应的方向在不同研究中存在差异。具体而言，在 14 项研究中，文化适应（表现为更倾向于宿主文化）与炎症生物标志物相关，在 20 项研究中与内分泌应激生物标志物相关，在 8 项研究中与综合 AL 评分相关。总体而言，基于语言的文化适应代理测量指标与应激相关炎症和内分泌生物标志物水平升高以及 AL 评分降低有关，而基于出生地、代际地位和居住时间的文化适应代理测量指标与炎症生物标志物和 AL 评分升高有关。
大多数研究报告了文化适应测量指标与应激生物标志物之间的关联，但效应的方向在不同研究中存在差异。我们认为，这种异质性可能部分是由于横断面研究设计和文化适应单维测量指标的限制所致，我们强调需要进行纵向研究并使用多维文化适应测量指标，以更好地揭示文化适应与健康结果之间的生物行为机制和途径。
