Kotey Fleischer Cn, Dayie Nicholas Tkd, Tetteh-Uarcoo Patience B, Donkor Eric S
Department of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra, Ghana.
FleRhoLife Research Consult, Teshie, Accra, Ghana.
Infect Dis (Auckl). 2021 Jun 24;14:11786337211026927. doi: 10.1177/11786337211026927. eCollection 2021.
The literature on bloodstream infections (BSIs) have predominantly been biased towards bacteria, given their superior clinical significance in comparison with the other types of microorganisms. Fungal pathogens have epidemiologically received relatively less attention, although they constitute an important proportion of BSI aetiologies. In this review, the authors discuss the clinical relevance of fungal BSIs in the context of species, as well as treatment options for the infections, emphasizing the compelling need to develop newer antifungals and strengthen antimicrobial stewardship programmes in the wake of the rapid spread of antifungal resistance.
鉴于与其他类型微生物相比，细菌在血流感染（BSIs）方面具有更高的临床意义，关于血流感染的文献主要偏向于细菌。尽管真菌病原体在血流感染病因中占重要比例，但在流行病学上受到的关注相对较少。在本综述中，作者讨论了真菌血流感染在物种背景下的临床相关性以及感染的治疗选择，强调在抗真菌耐药性迅速传播的情况下，迫切需要开发新型抗真菌药物并加强抗菌药物管理计划。
