Goldberger A L, West B J
Cardiovascular Division, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215.
Yale J Biol Med. 1987 Sep-Oct;60(5):421-35.
Nonlinear dynamics, a branch of the basic sciences that studies complex physical systems, offers novel approaches to long-standing problems of physiological form and function. The nonlinear concept of fractals, introduced and developed over the last decade, provides insights into the organization of complex structures such as the tracheobronchial tree and heart, as well as into the dynamics of healthy physiological variability. Alterations in fractal scaling may underlie a number of pathophysiological disturbances, including sudden cardiac death syndromes.
非线性动力学是基础科学的一个分支,研究复杂的物理系统,为长期存在的生理形态和功能问题提供了新的方法。在过去十年中引入并发展起来的分形的非线性概念,为诸如气管支气管树和心脏等复杂结构的组织以及健康生理变异性的动力学提供了见解。分形标度的改变可能是包括心脏性猝死综合征在内的许多病理生理紊乱的基础。