Goldberger A L
Harvard Medical School, Boston, MA 02215.
News Physiol Sci. 1991 Apr;6:87-91. doi: 10.1152/physiologyonline.1991.6.2.87.
Limits to the usefulness of homeostasis as a guiding physiological principle are revealed by new mechanisms derived from study of nonlinear systems that generate a type of variability called chaos. Loss of complex physiological variability may occur in certain pathological conditions including heart rate dynamics before sudden death and with aging.
作为一种指导生理原则,稳态的有用性存在局限,这一点已通过对非线性系统的研究揭示出的新机制得以显现,这些非线性系统会产生一种称为混沌的变异性。在某些病理状况下,包括猝死前的心率动态变化以及随着衰老过程,复杂的生理变异性可能会丧失。