Bigdelian Hamid, Sedighi Mohsen, Sabri Mohammad Reza, Dehghan Bahar, Mahdavi Chehreh, Ahmadi Alireza, Ghaderian Mehdi, Rahimi Hamid, Sadeghizadeh Atefeh, Emadoleslami Monirsadat, Mostafavi Seyed Nasser, Saleh Rana, Javadi Niloofar, Derakhshan Maryam, Pourmoghaddas Zahra, Sarfarazi Moghadam Shima
Department of Cardiovascular Surgery, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.
Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Front Pediatr. 2021 Jun 25;9:656720. doi: 10.3389/fped.2021.656720. eCollection 2021.
We herein describe a case series of children with SARS-CoV-2 infection (COVID-19) complicated with acute intracardiac thrombosis. The diagnosis of COVID-19 was confirmed through the reverse transcription-polymerase chain reaction (RT-PCR). Transthoracic echocardiography of patients revealed large intracardiac mobile masses resected successfully via cardiac surgery. The underlying mechanisms of this thrombus in the COVID-19 infection may be attributed to the hypercoagulation and inflammatory state of the disease incurred by the SARS-CoV-2 virus.
我们在此描述一系列感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)(新冠病毒病)并并发急性心内血栓形成的儿童病例。新冠病毒病的诊断通过逆转录聚合酶链反应(RT-PCR)得以证实。患者的经胸超声心动图显示心内有巨大活动团块,经心脏手术成功切除。新冠病毒病感染中这种血栓形成的潜在机制可能归因于SARS-CoV-2病毒引发的疾病的高凝状态和炎症状态。