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正常、高血压和糖尿病妊娠中人类胎儿心脏的生长与功能

Growth and function of human fetal heart in normal, hypertensive and diabetic pregnancy.

作者信息

Räsänen J, Kirkinen P

机构信息

Department of Obstetrics and Gynecology, University of Oulu, Finland.

出版信息

Acta Obstet Gynecol Scand. 1987;66(4):349-53. doi: 10.3109/00016348709103651.

DOI:10.3109/00016348709103651
PMID:3425231
Abstract

Fetal cardiac left and right ventricular dimensions and contractility were measured by echocardiography in late pregnancy in 51 normal, 26 hypertensive and 18 diabetic pregnancies. In relationship with the fetal size, both of the ventricular dimensions, the contractility and left ventricular output were decreased in diabetic cases. In hypertensive pregnancy the relative size of the right ventricle was increased and its contractility decreased, but the function of the left ventricle was no different from normal. These findings may reflect biochemical changes in diabetic myocardium and increased peripheral fetal and placental resistance in hypertensive pregnancy.

摘要

通过超声心动图测量了51例正常妊娠、26例高血压妊娠和18例糖尿病妊娠晚期胎儿的心脏左右心室尺寸及收缩性。与胎儿大小相关,糖尿病病例中两个心室的尺寸、收缩性及左心室输出量均降低。在高血压妊娠中,右心室的相对尺寸增大且其收缩性降低,但左心室功能与正常情况无异。这些发现可能反映了糖尿病心肌的生化变化以及高血压妊娠中胎儿和胎盘外周阻力的增加。

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