Newlin D B
Purdue University.
Adv Alcohol Subst Abuse. 1987 Summer;6(4):33-57. doi: 10.1300/J251v06n04_04.
This paper presents an overview of research performed in the context of a classical conditioning model of addiction to alcohol. College age sons of alcoholics were administered placebo in a single session or alcohol in repeated sessions in the laboratory. Sons of alcoholics had enhanced autonomic responses to placebo that were opposite in direction to the effect of alcohol, and they showed reverse tolerance to alcohol in three conditioning sessions. These studies are discussed in relation to theories of addiction to alcohol and a speculative model of risk for alcoholism.
本文概述了在酒精成瘾经典条件反射模型背景下所开展的研究。在实验室中，酗酒者处于大学年龄的儿子们接受了单次安慰剂给药或多次酒精给药。酗酒者的儿子们对安慰剂的自主反应增强，其方向与酒精的作用相反，并且他们在三个条件反射阶段对酒精表现出反向耐受性。本文结合酒精成瘾理论和酒精中毒风险推测模型对这些研究进行了讨论。
