Department of Otolaryngology, Kangwon National University Hospital, 156, Baengnyeong-ro, Chuncheon-Si, Gangwon-Do, 24289, Republic of Korea.
Department of Otolaryngology, Kangwon National University, Chuncheon, Korea.
Sleep Breath. 2022 Jun;26(2):847-853. doi: 10.1007/s11325-021-02431-y. Epub 2021 Jul 13.
The association between rhinosinusitis and obstructive sleep apnea (OSA) remains unclear. Here, we aimed to elucidate the association between sinus opacification and OSA severity.
Patients with snoring problems who visited our clinic from April 2018 to December 2020 were retrospectively enrolled. Among these patients, we included those who underwent a physical examination, overnight polysomnography, and osteomeatal-unit computed tomography. We evaluated the association between apnea-hypopnea index (AHI) and Lund-Mackay score (LMS). LMS ≥ 5 was considered indicative of sinus opacification.
Among the 122 patients included in the study, LMS exhibited an increasing trend based on OSA severity. The LMS in the moderate OSA group was significantly higher than that in the no OSA group (P = 0.002), and the LMS in the severe OSA group was significantly higher than that in the no OSA (P < 0.001) and mild OSA (P = 0.006) groups. A correlation analysis revealed that AHI was significantly associated with body mass index (BMI) (r = 0.367, P < 0.001) and LMS (r = 0.255, P = 0.005). A multivariate analysis revealed that sinus opacification was associated with moderate and severe OSA [Adjusted odds ratio = 11.986 (P = 0.005) and 3.756 (P = 0.044), respectively] after adjusting for age, sex, BMI, smoking, hypertension, atopy, tonsil size, and palatal position. The effect of sinus opacification on OSA severity was comparable to that of overweight.
Sinus opacification may increase OSA severity since moderate and severe OSA is independently associated with it.
鼻窦炎与阻塞性睡眠呼吸暂停（OSA）之间的关系尚不清楚。在这里，我们旨在阐明鼻窦混浊与 OSA 严重程度之间的关系。
回顾性纳入 2018 年 4 月至 2020 年 12 月期间因打鼾问题就诊于我院的患者。这些患者均接受了体格检查、夜间多导睡眠图和额窦-筛窦单元计算机断层扫描。我们评估了呼吸暂停低通气指数（AHI）与 Lund-Mackay 评分（LMS）之间的关系。LMS≥5 被认为是鼻窦混浊的指征。
在纳入研究的 122 例患者中，LMS 随着 OSA 严重程度呈上升趋势。中重度 OSA 组的 LMS 明显高于无 OSA 组（P=0.002），重度 OSA 组的 LMS 明显高于无 OSA 组（P<0.001）和轻度 OSA 组（P=0.006）。相关性分析显示，AHI 与体重指数（BMI）（r=0.367，P<0.001）和 LMS（r=0.255，P=0.005）显著相关。多变量分析显示，在调整年龄、性别、BMI、吸烟、高血压、特应性、扁桃体大小和腭位后，鼻窦混浊与中重度 OSA 相关[校正比值比（OR）分别为 11.986（P=0.005）和 3.756（P=0.044）]。鼻窦混浊对 OSA 严重程度的影响与超重相当。
由于中重度 OSA 与鼻窦混浊独立相关，因此鼻窦混浊可能会增加 OSA 严重程度。
