Pearson T A
Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Am J Cardiol. 1987 Dec 28;60(18):74J-79J. doi: 10.1016/0002-9149(87)90687-4.
The prevention of ischemic heart disease requires intervention on the natural history of coronary artery disease (CAD). Because a variety of so-called risk factors influence that natural history, it is logical to consider modification of these risk factors as a way to prevent CAD. Although this approach is effective in both the primary and secondary prevention of CAD, this presentation will focus on behavioral intervention on multiple risk factors in the secondary prevention of CAD (i.e., after the initial cardiac event). A number of studies have suggested that lifestyle modification plays an important role in preventing CAD recurrence or death. Risk factors that require this modification of human behavior include: low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, cigarette smoking, obesity, hypertension, physical activity and, although controversial, coronary prone personality. The assessment of these multiple factors can be performed in most acute care settings. The intervention on the factors requires a structured approach to the patient, taking advantage of the heightened awareness and concern at the time of a cardiac event. Often, several behaviors require modification simultaneously and other disciplines (behavioral medicine, nutrition, exercise physiology) are often useful when integrated into a single treatment plan. Involvement of the patient's social support network is essential. The effectiveness of the modification of each risk factor is assessed, as a means of recognizing behavior change as a way to prevent recurrence of the disease.
缺血性心脏病的预防需要对冠状动脉疾病(CAD)的自然病程进行干预。由于多种所谓的危险因素会影响其自然病程,因此将这些危险因素的改变作为预防CAD的一种方法是合乎逻辑的。尽管这种方法在CAD的一级预防和二级预防中均有效,但本报告将重点关注CAD二级预防(即初次心脏事件后)中针对多种危险因素的行为干预。多项研究表明,生活方式的改变在预防CAD复发或死亡方面起着重要作用。需要改变人类行为的危险因素包括:低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、吸烟、肥胖、高血压、身体活动,以及虽然存在争议但有患冠心病倾向的人格。在大多数急性护理环境中都可以对这些多种因素进行评估。对这些因素的干预需要针对患者采取结构化方法,利用心脏事件发生时提高的意识和关注度。通常,几种行为需要同时改变,并且当整合到单一治疗计划中时,其他学科(行为医学、营养学、运动生理学)通常会很有帮助。患者社会支持网络的参与至关重要。评估每种危险因素改变的有效性,作为将行为改变视为预防疾病复发的一种方式。