Charron J, Soto-Catalan C, Marcotte L'Heureux V, Comtois A S
Department of Exercise Science, University of Quebec in Montreal, Montreal, Canada.
Brain Inj. 2021 Jul 29;35(9):987-1000. doi: 10.1080/02699052.2021.1891459. Epub 2021 Jul 13.
: To systematically regroup articles that were published since the latest systematic search, but with specific inclusion criteria to help comparison that will offer a focused presentation of methods and results. This will offer a full overview of HRV's behavior at rest and during exercise in adults post-concussion.
: The systematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) method. A computer-based systematic search was conducted in December 2019 through the Pubmed, Scopus and SPORTDiscus databases. A manual search was performed through the reference list of all articles retained. The reliability of the systematic search was assured by having the article selection process entirely repeated by a second author.
: The systematic search yielded a total of 15 articles to be further analyzed. Results show impairment of HRV during exercise for individuals with concussion, heterogenous studies with lack of control over confounding factors and only less than half of the results showing a significant difference between individuals with concussion and controls.
: Further research should try standardizing HRV measurement protocols that control confounding factors to allow easier comparison between studies and allows the possibility for an eventual meta-analysis.
对自上次系统检索以来发表的文章进行系统重新分组，但采用特定纳入标准以助于比较，从而集中呈现方法和结果。这将全面概述成人脑震荡后静息和运动期间心率变异性（HRV）的表现。
采用系统评价与Meta分析的首选报告项目（PRISMA）方法进行系统评价。2019年12月通过PubMed、Scopus和SPORTDiscus数据库进行基于计算机的系统检索。通过对所有保留文章的参考文献列表进行手动检索。通过让第二位作者完全重复文章选择过程来确保系统检索的可靠性。
系统检索共产生15篇文章待进一步分析。结果显示，脑震荡患者运动期间HRV受损，研究存在异质性，对混杂因素缺乏控制，且只有不到一半的结果显示脑震荡患者与对照组之间存在显著差异。
进一步的研究应尝试规范HRV测量方案，控制混杂因素，以便于研究之间的比较，并为最终的Meta分析提供可能。
