From the Departments of Neuroradiology (J.E.S., A.B.P., M.K.)
Radiology (P.O), Lahey Hospital and Medical Center, Burlington, Massachusetts.
AJNR Am J Neuroradiol. 2021 Jul;42(7):1341-1347. doi: 10.3174/ajnr.A7094. Epub 2021 Apr 1.
Multidetector CT has emerged as the standard of care imaging technique to evaluate cervical spine trauma. Our aim was to evaluate the performance of a convolutional neural network in the detection of cervical spine fractures on CT.
We evaluated C-spine, an FDA-approved convolutional neural network developed by Aidoc to detect cervical spine fractures on CT. A total of 665 examinations were included in our analysis. Ground truth was established by retrospective visualization of a fracture on CT by using all available CT, MR imaging, and convolutional neural network output information. The ĸ coefficients, sensitivity, specificity, and positive and negative predictive values were calculated with 95% CIs comparing diagnostic accuracy and agreement of the convolutional neural network and radiologist ratings, respectively, compared with ground truth.
Convolutional neural network accuracy in cervical spine fracture detection was 92% (95% CI, 90%-94%), with 76% (95% CI, 68%-83%) sensitivity and 97% (95% CI, 95%-98%) specificity. The radiologist accuracy was 95% (95% CI, 94%-97%), with 93% (95% CI, 88%-97%) sensitivity and 96% (95% CI, 94%-98%) specificity. Fractures missed by the convolutional neural network and by radiologists were similar by level and location and included fractured anterior osteophytes, transverse processes, and spinous processes, as well as lower cervical spine fractures that are often obscured by CT beam attenuation.
The convolutional neural network holds promise at both worklist prioritization and assisting radiologists in cervical spine fracture detection on CT. Understanding the strengths and weaknesses of the convolutional neural network is essential before its successful incorporation into clinical practice. Further refinements in sensitivity will improve convolutional neural network diagnostic utility.
多排 CT 已成为评估颈椎创伤的标准影像学检查方法。我们旨在评估卷积神经网络在 CT 检测颈椎骨折方面的性能。
我们评估了 C-spine,这是由 Aidoc 开发的经 FDA 批准的卷积神经网络,用于在 CT 上检测颈椎骨折。我们的分析共纳入 665 例检查。通过使用所有可用的 CT、MR 成像和卷积神经网络输出信息,对骨折进行回顾性可视化,从而确定骨折的真实情况。使用 95%置信区间(CI)分别计算ĸ系数、敏感性、特异性、阳性和阴性预测值,以比较卷积神经网络和放射科医生的诊断准确性和一致性,以及与真实情况的一致性。
卷积神经网络在颈椎骨折检测中的准确率为 92%(95%CI,90%-94%),敏感性为 76%(95%CI,68%-83%),特异性为 97%(95%CI,95%-98%)。放射科医生的准确率为 95%(95%CI,94%-97%),敏感性为 93%(95%CI,88%-97%),特异性为 96%(95%CI,94%-98%)。卷积神经网络和放射科医生遗漏的骨折在水平和位置上相似,包括骨折的前骨赘、横突和棘突,以及因 CT 束衰减而常被掩盖的下颈椎骨折。
卷积神经网络在 CT 颈椎骨折检测的工作列表优先级设置和辅助放射科医生方面具有应用前景。在成功将其纳入临床实践之前,了解卷积神经网络的优势和劣势至关重要。进一步提高敏感性将提高卷积神经网络的诊断效用。