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[风湿性疾病的眼部表现]

[Ocular manifestations of Rheumatic diseases].

作者信息

Günther Janine, Max Regina, Lorenz Hanns-Martin

出版信息

Dtsch Med Wochenschr. 2021 Jul;146(13-14):882-889. doi: 10.1055/a-1272-9653. Epub 2021 Jul 13.

Abstract

Pain in the musculoskeletal system and in the joints is what comes to mind first when people talk about rheumatic diseases. However, rheumatic diseases are multisystem disorders that can affect every organ system. Therefore, ocular manifestations are common and can occur in almost every rheumatic disease. On the one hand, they can even precede musculoskeletal manifestations. On the other hand, they can remain unrecognized without a thorough ophthalmologic examination in some disease entities. Consequently, a close cooperation between medical specialties is warranted, to prevent permanent impairment in vision or consequential damage to organs or joints.The following article thus focuses on the most important ocular manifestations of rheumatic diseases. For example, we address keratoconjunctivitis sicca as a complication in many rheumatic disorders, which include rheumatoid arthritis and, most importantly, Sjogren's syndrome. Furthermore, we cover uveitis and associated diseases such as spondyloarthritis or sarcoidosis. Also, we discuss giant cell arteritis as a rheumatological emergency. All in all, we aim to give a synopsis of clinical presentations, important diagnostic measures, and current therapeutic options of the above-mentioned disorders.

摘要

当人们谈论风湿性疾病时,首先想到的是肌肉骨骼系统和关节的疼痛。然而,风湿性疾病是多系统疾病,可影响每个器官系统。因此,眼部表现很常见,几乎可出现在每种风湿性疾病中。一方面,眼部表现甚至可能先于肌肉骨骼表现出现。另一方面,在某些疾病中,如果没有全面的眼科检查,这些眼部表现可能未被发现。因此,医学专科之间密切合作是必要的,以防止视力永久性损害或器官或关节的继发性损伤。因此,以下文章重点关注风湿性疾病最重要的眼部表现。例如,我们将干燥性角结膜炎作为许多风湿性疾病(包括类风湿关节炎,最重要的是干燥综合征)的并发症进行阐述。此外,我们还涵盖葡萄膜炎及相关疾病,如脊柱关节炎或结节病。同时,我们讨论巨细胞动脉炎这一风湿科急症。总之,我们旨在概述上述疾病的临床表现、重要诊断措施和当前治疗选择。

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