Baldassano V F
Temple University Hospital, Department of Ophthalmology, Philadelphia, PA 19140, USA.
Curr Opin Ophthalmol. 1998 Dec;9(6):85-8. doi: 10.1097/00055735-199812000-00015.
Ocular manifestations of rheumatic disease are common and varied. The presentation of uveitis in psoriatic arthritis and inflammatory bowel disease differ from typical HLA-B27-associated uveitis. Giant cell arteritis continues to be a common cause of visual loss. Early diagnosis is crucial to limiting visual loss. Once visual loss has occurred, the need for oral versus intravenous steroids is controversial. Chronic uveitis associated with juvenile rheumatoid arthritis may be less prevalent than previously shown. However, poor visual outcomes continue to occur and efforts to identify visual prognosticators are being made. Ocular involvement in Behçet's disease, if untreated, leads to blindness. Azathioprine has been shown to improve visual prognosis. Concurrent central nervous system disease has been correlated to a poor visual prognosis.
风湿性疾病的眼部表现常见且多样。银屑病关节炎和炎症性肠病中的葡萄膜炎表现与典型的HLA - B27相关葡萄膜炎不同。巨细胞动脉炎仍然是视力丧失的常见原因。早期诊断对于限制视力丧失至关重要。一旦发生视力丧失，口服与静脉注射类固醇的必要性存在争议。与幼年类风湿关节炎相关的慢性葡萄膜炎可能不如先前显示的那么普遍。然而，不良的视力结局仍在发生，并且正在努力确定视力预后指标。白塞病若不治疗，眼部受累会导致失明。硫唑嘌呤已被证明可改善视力预后。并发中枢神经系统疾病与不良的视力预后相关。
