Department of Orthopaedic Surgery, Division of Adult Reconstruction, NYU Langone Health, 301 East 17th Street, New York, NY, 10003, USA.
Department of Orthopaedic Surgery and Rehabilitation Medicine, SUNY Downstate Health Science Center, New York, NY, USA.
Eur J Orthop Surg Traumatol. 2022 Aug;32(6):1055-1061. doi: 10.1007/s00590-021-03071-4. Epub 2021 Jul 14.
The clinical impact of postoperative venous thromboembolism (VTE) following total joint arthroplasty (TJA) remains unclear. In this study, we evaluate the effect of VTE following TJA on postoperative outcomes including discharge disposition, readmission rates, and revision rates.
We retrospectively reviewed all patients over the age of 18 who underwent primary, elective THA or TKA between 2013 and 2020. Patients were stratified into two cohorts based on whether or not they had a VTE following their procedure. Baseline patient demographics and clinical outcomes such as readmissions and revisions were collected. Propensity score matching was performed to limit significant demographic differences, while independent sample t-tests and Pearson's chi-squared test were used to compare outcomes of interest between the groups.
After propensity score matching, there were 109 patients in each cohort, representing a total of 218 patients for the matched comparison. Prior to matching, the VTE cohort was noted to have a significantly higher BMI than the non-VTE cohort (32.22 ± 6.27 vs 30.93 ± 32.04 kg/m, p = 0.032). All other patient demographics were similar. Compared to the non-VTE cohort, the VTE cohort was less likely to be discharged home (66.1% vs 80.7%; p = 0.021), had a higher rate of 90-day all-cause readmissions (27.5% vs 9.2%, p = 0.001), and a higher two-year revision rate (11.0% vs 0.9%, p = 0.003).
Patients with postoperative VTE were less likely to be discharged home and had higher 90-day readmission and two-year revision rates. Therefore, mitigating perioperative risk factors, initiating appropriate long-term anticoagulation, and maintaining close follow-up for patients with postoperative VTE may play significant roles in decreasing hospital costs and the economic burden to the healthcare system.
Retrospective Cohort Study.
全关节置换术后静脉血栓栓塞(VTE)的临床影响仍不清楚。在这项研究中,我们评估了 TJA 后 VTE 对包括出院安置、再入院率和翻修率在内的术后结局的影响。
我们回顾性分析了 2013 年至 2020 年间接受初次、择期 THA 或 TKA 的年龄在 18 岁以上的所有患者。根据术后是否发生 VTE,将患者分为两组。收集基线患者人口统计学和临床结局,如再入院和翻修。采用倾向评分匹配来限制显著的人口统计学差异,同时采用独立样本 t 检验和 Pearson 卡方检验比较两组间感兴趣的结局。
在倾向评分匹配后,每组各有 109 例患者,共 218 例患者进行了匹配比较。在匹配前,VTE 组的 BMI 明显高于非 VTE 组(32.22±6.27 与 30.93±32.04 kg/m,p=0.032)。所有其他患者的人口统计学特征相似。与非 VTE 组相比,VTE 组更不可能出院回家(66.1%与 80.7%;p=0.021),90 天全因再入院率更高(27.5%与 9.2%,p=0.001),两年翻修率更高(11.0%与 0.9%,p=0.003)。
术后发生 VTE 的患者更不可能出院回家,90 天再入院率和两年翻修率更高。因此,减轻围手术期危险因素、对术后 VTE 患者及时启动适当的长期抗凝治疗并进行密切随访,可能对降低医院成本和医疗系统的经济负担起到重要作用。
证据等级 III:回顾性队列研究。