School of Medicine, University of Liverpool, Cedar House, Ashton Street, L69 3GE Liverpool, UK.
Department of Cardiothoracic Surgery, Liverpool Heart and Chest, L14 3PE Liverpool, UK.
Rev Cardiovasc Med. 2021 Jun 30;22(2):329-341. doi: 10.31083/j.rcm2202040.
Post-operative Atrial fibrillation (POAF) is a common complication post cardiac surgery. It can result in detrimental short- and long-term outcomes due to the increased risk of stroke, cardiac arrest and congestive heart failure in addition to prolonged intensive care and total hospital stay raising the overall healthcare cost. Accurately identifying predictors and biomarkers for POAF ensures that patients at greatest risk can be given the appropriate prophylactic measures; resources can be distributed to the groups who are most in need and where they will gain the optimum effect. Commonly recurring predictors can be investigated further to unveil the pathophysiology behind POAF, which has yet to be fully understood. This literature review aims to examine relevant studies on the proposed predictors of POAF: increased age, gender, history of atrial fibrillation, hypertension, cardiopulmonary bypass time and the use of beta blockers amongst others. This paper will discuss the significance of both the well-known and newfound risk factors to consolidate the areas that require further exploration in order to highlight those at risk and to unravel the mechanism behind POAF.
术后心房颤动（POAF）是心脏手术后的一种常见并发症。由于中风、心脏骤停和充血性心力衰竭的风险增加，以及重症监护和总住院时间延长，导致短期和长期预后不佳，从而增加了整体医疗保健成本。准确识别 POAF 的预测因素和生物标志物可确保给予风险最大的患者适当的预防措施；资源可以分配给最需要的人群，并在那里获得最佳效果。常见的复发性预测因素可以进一步研究，以揭示 POAF 背后的病理生理学，目前尚未完全了解。本文献综述旨在检查关于 POAF 拟议预测因素的相关研究：年龄增长、性别、心房颤动史、高血压、体外循环时间和使用β受体阻滞剂等。本文将讨论知名和新发现的风险因素的意义，以整合需要进一步探索的领域，以突出风险人群，并揭示 POAF 背后的机制。
