Independent predictors of in-hospital and 1-year mortality rates in octogenarians with acute myocardial infarction.

Older age is known as a negative prognostic parameter in acute myocardial infarction (AMI) patients. In this study, we aimed to explore age-associated differences in treatment protocols, in-hospital and 1-year mortality. This cohort observational study included 277 consecutive AMI patients, separated into 2 groups according to whether their age was ≥80 years or not. We found that group I patients (aged ≥80 years) had a notably lower rate of percutaneous coronary intervention (PCI) performed ( < 0.0001) and a notably higher in-hospital death rate ( < 0.003). The multivariate logistic regression analysis found that three variables were independent predictors of in-hospital mortality: age ≥80 years ( < 0.0001), LVEF <40% ( < 0.0001), and Killip class ≥3 ( < 0.0001). The 1-year death rate was again significantly higher in group I patients ( < 0.001) and was independently predicted by the triple-vessel coronary artery disease ( = 0.004) and an LVEF <40% at admission ( = 0.001). The 1-year readmission rate was superior in group I ( < 0.01) and independently predicted by an age ≥80 years ( < 0.001), and an history of congestive heart failure ( < 0.0001) or permanent atrial fibrillation ( < 0.001). We concluded that patients aged ≥80 benefit less often from a PCI and have higher rates of in-hospital mortality, as well as of 1-year readmission and mortality rates.