Clin Lab. 2021 Jul 1;67(7). doi: 10.7754/Clin.Lab.2020.201133.
We aimed to investigate the associations between glycemic biomarkers (hemoglobin A1c [HbA1c], fructosamine, and glycated albumin [GA]) in Korean adults.
We retrospectively reviewed data for HbA1c, fructosamine, and glycated albumin between August 28, 2017, and June 30, 2020, to investigate the association between HbA1c and fructosamine and between HbA1c and GA.
Overall, 961 fructosamine and 142 GA tests concurrently measured HbA1c. The equations were HbA1c (%) = 0.0175 x fructosamine (µmol/L) + 1.6255 and HbA1c (%) = 0.2029 x GA + 2.8102, respectively. The absolute difference between estimated and measured HbA1c ranged from -3.4% to 2.1% HbA1c with the fructosamine equation and -3.2% to 2.8% HbA1c with the GA equation.
Fructosamine and GA may be useful adjuncts to HbA1c in Korean patients.
本研究旨在探讨韩国成年人血糖生物标志物（糖化血红蛋白 [HbA1c]、果糖胺和糖化白蛋白 [GA]）之间的相关性。
我们回顾性分析了 2017 年 8 月 28 日至 2020 年 6 月 30 日期间 HbA1c、果糖胺和 GA 的数据，以调查 HbA1c 与果糖胺和 HbA1c 与 GA 之间的相关性。
共同时检测了 961 次果糖胺和 142 次 GA 测试 HbA1c。相应的方程分别为 HbA1c（%）= 0.0175 x 果糖胺（µmol/L）+ 1.6255 和 HbA1c（%）= 0.2029 x GA + 2.8102。果糖胺方程的估计 HbA1c 与实测 HbA1c 的绝对差值范围为-3.4%至 2.1%HbA1c，GA 方程的差值范围为-3.2%至 2.8%HbA1c。
果糖胺和 GA 可能是韩国患者 HbA1c 的有用补充指标。
