Harvard Medical School, Boston, Massachusetts.
Department of Pediatrics-General Pediatrics, Massachusetts General Hospital for Children, Boston.
JAMA Netw Open. 2021 Jul 1;4(7):e2117115. doi: 10.1001/jamanetworkopen.2021.17115.
Social distancing is critical to the control of COVID-19, which has disproportionately affected the Black community. Physician-delivered messages may increase adherence to these behaviors.
To determine whether messages delivered by physicians improve COVID-19 knowledge and preventive behaviors and to assess the differential effectiveness of messages tailored to the Black community.
DESIGN, SETTING, AND PARTICIPANTS: This randomized clinical trial of self-identified White and Black adults with less than a college education was conducted from August 7 to September 6, 2020. Of 44 743 volunteers screened, 30 174 were eligible, 5534 did not consent or failed attention checks, and 4163 left the survey before randomization. The final sample had 20 460 individuals (participation rate, 68%). Participants were randomly assigned to receive video messages on COVID-19 or other health topics.
Participants saw video messages delivered either by a Black or a White study physician. In the control groups, participants saw 3 placebo videos with generic health topics. In the treatment group, they saw 3 videos on COVID-19, recorded by several physicians of varied age, gender, and race. Video 1 discussed common symptoms. Video 2 highlighted case numbers; in one group, the unequal burden of the disease by race was discussed. Video 3 described US Centers for Disease Control and Prevention social distancing guidelines. Participants in both the control and intervention groups were also randomly assigned to see 1 of 2 American Medical Association statements, one on structural racism and the other on drug price transparency.
Knowledge, beliefs, and practices related to COVID-19, demand for information, willingness to pay for masks, and self-reported behavior.
Overall, 18 223 participants (9168 Black; 9055 White) completed the survey (9980 [55.9%] women, mean [SD] age, 40.2 [17.8] years). Overall, 6303 Black participants (34.6%) and 7842 White participants (43.0%) were assigned to the intervention group, and 1576 Black participants (8.6%) and 1968 White participants (10.8%) were assigned to the control group. Compared with the control group, the intervention group had smaller gaps in COVID-19 knowledge (incidence rate ratio [IRR], 0.89 [95% CI, 0.87-0.91]) and greater demand for COVID-19 information (IRR, 1.05 [95% CI, 1.01-1.11]), willingness to pay for a mask (difference, $0.50 [95% CI, $0.15-$0.85]). Self-reported safety behavior improved, although the difference was not statistically significant (IRR, 0.96 [95% CI, 0.92-1.01]; P = .08). Effects did not differ by race (F = 0.0112; P > .99) or in different intervention groups (F = 0.324; P > .99).
In this study, a physician messaging campaign was effective in increasing COVID-19 knowledge, information-seeking, and self-reported protective behaviors among diverse groups. Studies implemented at scale are needed to confirm clinical importance.
ClinicalTrials.gov Identifier: NCT04502056.
社交距离对于控制 COVID-19 至关重要,COVID-19 对黑人社区的影响不成比例。医生传达的信息可能会增加对这些行为的遵守。
确定医生传达的信息是否能提高 COVID-19 知识和预防行为,并评估针对黑人社区的信息的差异效果。
设计、地点和参与者:这是一项针对自我认定为受过大学以下教育的白人和黑人成年人的随机临床试验,于 2020 年 8 月 7 日至 9 月 6 日进行。在筛选的 44743 名志愿者中,有 30464 名符合条件,5534 名不同意或未通过注意力检查,4163 名在随机分组前退出调查。最终样本有 20460 人(参与率为 68%)。参与者被随机分配接受 COVID-19 或其他健康主题的视频信息。
参与者观看由黑人或白人研究医生提供的视频信息。在对照组中,参与者观看了 3 个带有通用健康主题的安慰剂视频。在治疗组中,他们观看了 3 个由不同年龄、性别和种族的几位医生录制的关于 COVID-19 的视频。视频 1 讨论了常见症状。视频 2 强调了病例数量;在一个组中,讨论了疾病在种族间的不平等负担。视频 3 描述了美国疾病控制与预防中心的社会距离准则。控制组和干预组的参与者也被随机分配观看美国医学协会的 2 个声明中的 1 个,一个关于结构性种族主义,另一个关于药物价格透明度。
与 COVID-19 相关的知识、信仰和行为,对信息的需求,愿意为口罩付费,以及自我报告的行为。
总体而言,18223 名参与者(9168 名黑人;9055 名白人)完成了调查(9980 [55.9%] 名女性,平均[SD]年龄 40.2 [17.8] 岁)。总的来说,6303 名黑人参与者(34.6%)和 7842 名白人参与者(43.0%)被分配到干预组,1576 名黑人参与者(8.6%)和 1968 名白人参与者(10.8%)被分配到对照组。与对照组相比,干预组在 COVID-19 知识方面的差距较小(发病率比[IRR],0.89 [95%CI,0.87-0.91]),对 COVID-19 信息的需求更大(IRR,1.05 [95%CI,1.01-1.11]),愿意为口罩付费(差异,0.50 美元[95%CI,0.15-0.85])。自我报告的安全行为有所改善,尽管差异不具有统计学意义(IRR,0.96 [95%CI,0.92-1.01];P=0.08)。效果不因种族(F=0.0112;P>.99)或不同的干预组(F=0.324;P>.99)而有所不同。
在这项研究中,医生信息传递活动在不同群体中有效提高了 COVID-19 知识、信息寻求和自我报告的保护行为。需要进行大规模实施的研究来确认临床重要性。
ClinicalTrials.gov 标识符:NCT04502056。