Schubert Steffen, Bauer Andrea, Hillen Uwe, Werfel Thomas, Geier Johannes, Brans Richard
Information Network of Departments of Dermatology (IVDK), Institute at the University Medical Center Göttingen, Göttingen, Germany.
Department of Dermatology, University Allergy Center, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Contact Dermatitis. 2021 Nov;85(5):494-502. doi: 10.1111/cod.13935. Epub 2021 Aug 12.
Painters and varnishers ("painters") are exposed to various contact allergens and skin irritants, and therefore, are at risk for developing occupational dermatitis (OD).
To describe the spectrum of occupational sensitizations in painters and revise the corresponding current patch test recommendations.
Retrospective analysis of Information Network of Departments of Dermatology (IVDK) data from 2000 to 2019 with focus on male painters with OD, ages 20-59 years (n = 557) in comparison to age-matched male painters without OD (n = 422) and male OD patients who have had never worked as painters (n = 13 862).
Male painters with OD have a significantly higher rate of allergic contact dermatitis and face dermatitis than male patients with OD who work in other professions. Positive patch tests to epoxy resin, methylisothiazolinone (MI), and methylchloroisothiazolinone (MCI)/MI were significantly more frequent in painters with OD than in the other groups. Epoxy resin sensitization was significantly associated with face dermatitis.
Epoxy resin, MI, and MCI/MI represent the most important occupational sensitizers in painters. In addition to baseline, resins and glues, and industrial biocides series, the patients' own workplace materials should be tested in painters with suspected OD.
油漆工和清漆工(“油漆工”)会接触到各种接触性变应原和皮肤刺激物,因此有患职业性皮炎(OD)的风险。
描述油漆工职业致敏的范围,并修订相应的当前斑贴试验建议。
对皮肤病科信息网络(IVDK)2000年至2019年的数据进行回顾性分析,重点关注年龄在20 - 59岁的患有OD的男性油漆工(n = 557),并与年龄匹配的无OD的男性油漆工(n = 422)以及从未从事过油漆工工作的男性OD患者(n = 13862)进行比较。
患有OD的男性油漆工发生过敏性接触性皮炎和面部皮炎的比率显著高于从事其他职业的患有OD的男性患者。患有OD的油漆工对环氧树脂、甲基异噻唑啉酮(MI)和甲基氯异噻唑啉酮(MCI)/MI的斑贴试验阳性率明显高于其他组。环氧树脂致敏与面部皮炎显著相关。
环氧树脂、MI和MCI/MI是油漆工最重要的职业致敏原。除了基线的树脂和胶水以及工业杀菌剂系列外,对于疑似患有OD的油漆工,还应检测其工作场所的材料。