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抗菌光动力和光生物调节辅助疗法治疗肛周脓肿。

Antimicrobial photodynamic and photobiomodulation adjuvant therapies for the treatment of perianal abscess.

机构信息

Service of Gynecology, Hospital São Luiz, São Paulo, SP, Brazil; Private office, CAMPE, São Paulo, SP, Brazil.

Private office, CAMPE, São Paulo, SP, Brazil; Service of Dermatology, Hospital São Camilo, São Paulo, SP, Brazil.

出版信息

Photodiagnosis Photodyn Ther. 2021 Sep;35:102437. doi: 10.1016/j.pdpdt.2021.102437. Epub 2021 Jul 11.

Abstract

Although the treatment and management options for perianal abscess vary considerably, most cases require incision and drainage. Whatever the clinical approach selected, it is imperative to monitor patients to identify postoperative signs and symptoms which suggest treatment failure or further complications, such as sepsis, recurrent abscess, and fistula formation. Considering the debate on the role of postoperative antibiotic therapy for patients with perianal abscess and the significant discomfort caused by the infection, the present study aimed to report a clinical case in which antimicrobial photodynamic therapy (aPDT) and photobiomodulation therapy (PBMT) were used after incision and drainage of a simple perianal abscess. Within 5 days, there was no sign or symptom of both infection and inflammation, and after 3 months, no fistulous pathways or perianal collections were present. According to the current case report, the combination of aPDT and PBMT following incision and drainage of perianal abscess may be a smart strategy for infection resolution and prevention of late complications.

摘要

尽管肛周脓肿的治疗和管理方法差异很大,但大多数情况下需要进行切开引流。无论选择何种临床方法,都必须对患者进行监测,以识别术后出现的提示治疗失败或进一步并发症的迹象和症状,如脓毒症、脓肿复发和瘘管形成。鉴于对肛周脓肿患者术后抗生素治疗作用的争议以及感染引起的明显不适,本研究旨在报告一例单纯肛周脓肿切开引流后采用抗菌光动力疗法(aPDT)和光生物调节疗法(PBMT)的临床病例。在 5 天内,既没有感染和炎症的迹象或症状,在 3 个月后,也没有瘘管或肛周积液。根据目前的病例报告,肛周脓肿切开引流后联合应用 aPDT 和 PBMT 可能是一种解决感染和预防晚期并发症的明智策略。

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