Terrenato L, Novelletto A
Galton Laboratory, University College London.
Ann Hum Genet. 1986 Jan;50(1):63-8. doi: 10.1111/j.1469-1809.1986.tb01939.x.
In the present paper the secular trend of twin concordance for late fetal death rate has been analysed. The results show that, while the correlation remains unchanged in MZ twins, it is greatly reduced in DZ twins. This renders untenable the assumption of comparable secular trends in the intrauterine environment of the two types of twins. An appropriate model is given for the estimation of the environmental (intrauterine) factors in late fetal concordance, under the assumption of a wide range of frequencies for unconditional lethals.
在本文中,对双胎晚期胎儿死亡率的长期趋势进行了分析。结果表明,虽然同卵双胞胎的相关性保持不变,但异卵双胞胎的相关性大幅降低。这使得关于两种类型双胞胎子宫内环境具有可比长期趋势的假设站不住脚。在无条件致死率频率范围广泛的假设下,给出了一个合适的模型来估计晚期胎儿一致性中的环境(子宫内)因素。