乳腺癌的放射性药物和放射性核素治疗：当前选择
Treatment with Radiopharmaceuticals and Radionuclides in Breast Cancer: Current Options.
作者信息
Altıparmak Güleç Burcu, Yurt Fatma
机构信息
Department of Nuclear Applications, Institute of Nuclear Science, Ege University, İzmir, Turkey (Graduated).
Department of Nuclear Applications, Institute of Nuclear Science, Ege University, İzmir, Turkey.
出版信息
Eur J Breast Health. 2021 Jun 24;17(3):214-219. doi: 10.4274/ejbh.galenos.2021.2021-3-4. eCollection 2021 Jul.
Abstract
Radiopharmaceutical therapy (RPT) is an effective and safe treatment for many types of cancer. RPT acts by binding radioactive atoms to tumor-associated antigens, monoclonal antibodies, nanoparticles, peptides, and small molecules. These treatments ensure that a concentrated dose is delivered to the targeted tumor tissue while preserving the normal tissues surrounding the tumor. Given these features, RPT is superior to traditional methods. This review article aimed to performa comprehensive review and evaluation of the potential of radionuclides and radiopharmaceuticals used in breast cancer treatment in preclinical studies conducted in the last five years.
摘要
放射性药物治疗（RPT）是一种针对多种癌症的有效且安全的治疗方法。RPT通过将放射性原子与肿瘤相关抗原、单克隆抗体、纳米颗粒、肽和小分子结合来发挥作用。这些治疗方法可确保在保护肿瘤周围正常组织的同时，将高剂量药物输送到靶向肿瘤组织。鉴于这些特性，RPT优于传统方法。这篇综述文章旨在对过去五年进行的临床前研究中用于乳腺癌治疗的放射性核素和放射性药物的潜力进行全面综述和评估。
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