Suppr超能文献

7 岁男孩患甲状腺乳头状癌,表现为甲状腺肿,无微钙化和颈淋巴结肿大。

Papillary thyroid carcinoma in a 7-year-old boy presenting with a goitre without microcalcifications and enlarged cervical lymph nodes.

机构信息

Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg.

Pediatric Endocrinology and Diabetology Unit, Centro Hospitalar Universitario de Sao Joao, Porto, Portugal.

出版信息

BMJ Case Rep. 2021 Jul 15;14(7):e242278. doi: 10.1136/bcr-2021-242278.

Abstract

The most frequent type of thyroid malignancy in children is papillary thyroid carcinoma (PTC), which usually presents as a thyroid nodule, but may also present as a diffuse infiltration with microcalcifications. Herein, we report the case of an uncommon presentation of a PTC in a 7-year-old boy. The child was referred for a goiter with cervical lymphadenopathies. Ultrasonography showed a hypervascularised goiter without microcalcifications but with numerous bilateral cervical nodular formations. A lymph node biopsy revealed metastatic thyroid cancer, hence a total thyroidectomy and complete neck dissection were performed. Histopathology confirmed a PTC. Ablative I, 30 mCi was performed 4 months postsurgery. At the end of this treatment, a metastatic lung nodule was identified. Since then, another three ablative I treatments have been administered. Thyroid cancers presenting as a diffuse infiltration without microcalcifications are rare. In the presence of lymphadenopathies, thyroid cancer needs to be suspected, even without microcalcifications.

摘要

儿童最常见的甲状腺恶性肿瘤是甲状腺乳头状癌(PTC),通常表现为甲状腺结节,但也可能表现为弥漫性浸润伴微钙化。本文报道了一例 7 岁男孩罕见的 PTC 表现。患儿因甲状腺肿伴颈部淋巴结病就诊。超声显示甲状腺肿呈多血管化,无微钙化,但有许多双侧颈部结节形成。淋巴结活检显示转移性甲状腺癌,因此行甲状腺全切除术和颈淋巴结清扫术。组织病理学证实为 PTC。术后 4 个月行 I 治疗 30mCi。在治疗结束时,发现一个转移性肺结节。此后,又进行了三次 I 治疗。不伴微钙化的弥漫性浸润性甲状腺癌很少见。存在淋巴结病时,即使没有微钙化,也需要怀疑甲状腺癌。

相似文献

4
Papillary thyroid cancer: controversies in the management of neck metastasis.
Laryngoscope. 2008 Dec;118(12):2161-5. doi: 10.1097/MLG.0b013e31818550f6.
6
Sonographic features of cervical lymph nodes after thyroidectomy for papillary thyroid carcinoma.
J Ultrasound Med. 2013 Jul;32(7):1173-80. doi: 10.7863/ultra.32.7.1173.
8
[Prediction and investigation of the potential risk factors for the upper mediastinal metastasis of papillary thyroid carcinoma].
Zhonghua Zhong Liu Za Zhi. 2021 Apr 23;43(4):477-483. doi: 10.3760/cma.j.cn112152-20200617-00569.
9
[Clinical study on papillary thyroid carcinoma presenting with lymph node metastasi].
Nihon Jibiinkoka Gakkai Kaiho. 2004 Aug;107(8):750-5. doi: 10.3950/jibiinkoka.107.750.
10
Papillary Thyroid Carcinoma in Children: Clinicopathological Profile and Outcomes of Management.
World J Surg. 2021 Feb;45(2):496-506. doi: 10.1007/s00268-020-05817-3. Epub 2020 Oct 19.

本文引用的文献

2
Pediatric papillary thyroid cancer: current management challenges.
Onco Targets Ther. 2016 Dec 28;10:165-175. doi: 10.2147/OTT.S100512. eCollection 2017.
3
4
Thyroid nodules in pediatrics: which ones can be left alone, which ones must be investigated, when and how.
J Clin Res Pediatr Endocrinol. 2013;5 Suppl 1(Suppl 1):57-69. doi: 10.4274/jcrpe.853.
5
Management of thyroid carcinoma in children and young adults.
J Pediatr Hematol Oncol. 2012 May;34 Suppl 2:S39-46. doi: 10.1097/MPH.0b013e31824e37a6.
6
Pediatric endocrine surgery: who is operating on our children?
Surgery. 2008 Dec;144(6):869-77; discussion 877. doi: 10.1016/j.surg.2008.08.033.
7
Differentiated thyroid cancer in children: diagnosis and management.
Curr Opin Oncol. 2008 Jan;20(1):59-65. doi: 10.1097/CCO.0b013e3282f30220.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验