Saint-Petersburg State Research Institute of Phthisiopulmonology, Saint-Petersburg, Russian Federation.
Saint-Petersburg State University, Medical Faculty, Saint-Petersburg, Russian Federation.
Adv Respir Med. 2021;89(4):456-459. doi: 10.5603/ARM.a2021.0067. Epub 2021 Jul 16.
Probe-based confocal laser endomicroscopy (pCLE) is a method that produces microscopic imaging of a lung tissue during bronchoscopy. We report a case ot a patient with negative nasopharyngeal swabs and suspected lung cancer who underwent pCLE. The diagnosis of COVID-19 was confirmed by PCR analyses of lavage fluid and transbrohial biopsy. The pCLE image shows density of alveolar thickened fibres, disorganization of elastin network, and multiple large drops of intraalveolar secretions. As far as we know, this is the first pCLE image discribed in patient with COVID-19 at that moment.
基于探针的共聚焦激光内镜检查（pCLE）是一种在支气管镜检查期间对肺组织进行微观成像的方法。我们报告了一例鼻咽拭子阴性且疑似肺癌的患者进行 pCLE 的病例。COVID-19 的诊断通过灌洗液和经支气管活检的 PCR 分析得到确认。pCLE 图像显示肺泡增厚纤维的密度增加、弹力蛋白网络的紊乱以及多个大的肺泡内分泌物液滴。据我们所知，这是当时首例描述 COVID-19 患者的 pCLE 图像。
