Elberg J J, Brandrup F
Department of Dermatology, Odense University Hospital, Denmark.
Br J Dermatol. 1987 Dec;117(6):745-50. doi: 10.1111/j.1365-2133.1987.tb07355.x.
Dermatome shaving was performed in 20 patients with chronic recalcitrant plaque psoriasis. The level of shaving was just beneath the superficial dermal vascular plexus. Healing was achieved in 2 weeks. After 1 year, six patients had shown no recurrence; 10 patients had a few guttate elements in the shaved area, while four patients had significant recurrence. Recurrences were related to residual acanthotic epidermis left after shaving. A general recommendation of surgical treatment for psoriasis would be hazardous on the basis of these results. However, shaving may constitute an alternative treatment of recalcitrant plaques of limited extent.
对20例慢性顽固性斑块状银屑病患者进行了皮片削除术。削除的深度刚好在真皮浅层血管丛下方。两周内实现愈合。1年后,6例患者未复发;10例患者在削除区域有一些点滴状皮损,而4例患者有明显复发。复发与削除术后残留的棘层肥厚表皮有关。基于这些结果,对银屑病进行手术治疗的一般建议是有风险的。然而,皮片削除术可能构成对局限性顽固性斑块的一种替代治疗方法。