68Ga-FAPI PET/CT 显示的门脉 biliopathy 和门脉海绵样变性。

Portal Biliopathy and Cavernous Transformation of the Portal Vein Revealed by 68Ga-FAPI PET/CT.

机构信息

Departments of Thoracic Surgery.

General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

Clin Nucl Med. 2022 Feb 1;47(2):161-163. doi: 10.1097/RLU.0000000000003815.

DOI:10.1097/RLU.0000000000003815

PMID:34269727

Abstract

A 47-year-old man presented with right upper abdominal pain for 1 month. Contrast-enhanced CT revealed hilar bile duct stenosis with dilatation of the intrahepatic bile ducts, and his serum CA19-9 and CA242 levels were significantly elevated. 18F-FDG and 68Ga-FAPI PET/CT were performed for differential diagnosis. 18F-FDG PET/CT showed only mild FDG uptake in the hepatic hilum. Astonishingly, in 68Ga-FAPI PET/CT, intense radioactivity was presented on the same region, which indicated massive fibroblasts aggregation in hepatic hilum. The patient was finally diagnosed as portal biliopathy caused by cavernous transformation of the portal vein.

摘要

一位 47 岁男性因右上腹疼痛就诊，病史 1 个月。增强 CT 显示肝门胆管狭窄伴肝内胆管扩张，血清 CA19-9 和 CA242 水平显著升高。为明确诊断，行 18F-FDG 和 68Ga-FAPI PET/CT 检查。18F-FDG PET/CT 仅显示肝门处 FDG 摄取轻度增加。令人惊讶的是，在 68Ga-FAPI PET/CT 上，同一区域显示出强烈的放射性，提示肝门处大量成纤维细胞聚集。患者最终被诊断为门静脉海绵样变所致的门管性胆管病。