From the Departments of Nuclear Medicine.
Pathology.
Clin Nucl Med. 2021 Dec 1;46(12):e594-e597. doi: 10.1097/RLU.0000000000003673.
A 56-year-old woman presented with abdominal pain and vomiting. Her abdominal CT revealed an retroperitoneal mass in the left upper quadrant of the abdomen. 18F-FDG PET/CT performed for metabolic characterization showed low to moderate heterogenous FDG uptake. 68Ga-fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT performed according to a research carried out in our department showed high heterogenous radiopharmaceutical uptake. The patient was diagnosed with leiomyosarcoma after R0 tumor resection. This case showed that 68Ga-FAPI-04 PET/CT could be a promising radiopharmaceutical in the evaluation of leiomyosarcomas.
一位 56 岁女性因腹痛和呕吐就诊。她的腹部 CT 显示左上腹部有腹膜后肿块。为了进行代谢特征分析,对其进行了 18F-FDG PET/CT 检查,结果显示为低到中度不均匀 FDG 摄取。根据我们科室进行的一项研究,对其进行了 68Ga-成纤维细胞活化蛋白特异性抑制剂(FAPI)-04 PET/CT 检查,结果显示为高不均匀放射性药物摄取。患者在进行 RO 肿瘤切除术后被诊断为平滑肌肉瘤。该病例表明,68Ga-FAPI-04 PET/CT 可能成为评估平滑肌肉瘤的一种很有前途的放射性药物。