School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.
Sports Medicine Center, Children's Hospital Colorado, Aurora, CO, USA; Department of Orthopedics, University of Colorado School of Medicine, Aurora, CO, USA; The Micheli Center for Sports Injury Prevention, Waltham, MA, USA.
Phys Ther Sport. 2021 Sep;51:71-78. doi: 10.1016/j.ptsp.2021.06.011. Epub 2021 Jun 30.
To prospectively investigate the condition-specific health-related quality of life (HRQoL) of athletes six months and one-year following sport-related concussion.
Prospective, longitudinal study.
Clinical research centre at university school of public health.
Amateur athletes who were diagnosed with sport-related concussion within one-week after presenting to a hospital emergency department were recruited along with sex-, age-, and activity-matched, non-concussed, control athletes. Concussion and control participants were assessed six months and one-year following sport-related concussion and study enrolment, respectively.
Participants completed the Post-Concussion Symptom Scale and five condition-specific HRQoL patient-reported outcome measures - Headache Impact Test-6, Fatigue Severity Scale, Neck Disability Index, Generalised Anxiety Disorder-7, and Dizziness Handicap Inventory. We performed Frequentist and Bayesian mixed-design analyses of variance to compare the concussion group and control group at both assessments and quantify whether there was greater evidence in favour of the null hypothesis compared with the alternative hypothesis.
At six-month and one-year assessments, the concussion group (n = 47; male = 72%; mean (SD) age = 22.68 (5.07)) and the control group (n = 47; male = 72%; mean (SD) age = 23.81 (4.60)) reported similar clinical symptom severity scores and condition-specific HRQoL. The proportion of athletes in the concussion group with clinically-impaired scores was similar to the proportion of non-concussed athletes with clinically-impaired scores. At six-month and one-year assessments, there was moderate-to-very strong evidence that there was no difference between concussion and control participants' perceptions of the effects of headache, fatigue, neck pain, anxiety, and dizziness on HRQoL.
There was moderate-to-very strong evidence in favour of no difference between the concussion and control groups on symptom severity scores and condition-specific HRQoL patient-reported outcome measures at six-month and one-year assessments. These results suggest that condition-specific HRQoL returns to the levels of non-concussed individuals within six months following sport-related concussion.
前瞻性研究与运动相关的脑震荡后 6 个月和 1 年运动员特定健康相关生活质量（HRQoL）的状况。
前瞻性、纵向研究。
大学公共卫生学院临床研究中心。
在医院急诊室就诊后一周内被诊断为与运动相关的脑震荡的业余运动员与性别、年龄和活动匹配、未受脑震荡的对照组运动员一起招募。脑震荡和对照组参与者分别在与运动相关的脑震荡和研究入组后 6 个月和 1 年进行评估。
参与者完成了脑震荡后症状量表和五个特定于疾病的 HRQoL 患者报告的结果测量 - 头痛影响测试-6、疲劳严重程度量表、颈部残疾指数、广泛性焦虑症-7 和头晕障碍量表。我们使用 Frequentist 和 Bayesian 混合设计方差分析比较了两个评估时的脑震荡组和对照组，并量化了与替代假设相比，零假设的证据是否更大。
在 6 个月和 1 年的评估中，脑震荡组（n=47；男性=72%；平均（SD）年龄=22.68（5.07））和对照组（n=47；男性=72%；平均（SD）年龄=23.81（4.60））报告了相似的临床症状严重程度评分和特定于疾病的 HRQoL。脑震荡组中有临床受损评分的运动员比例与非脑震荡运动员中有临床受损评分的运动员比例相似。在 6 个月和 1 年的评估中，有中度到非常强的证据表明，脑震荡和对照组参与者对头痛、疲劳、颈部疼痛、焦虑和头晕对 HRQoL 的影响的看法没有差异。
在 6 个月和 1 年的评估中，脑震荡组和对照组在症状严重程度评分和特定于疾病的 HRQoL 患者报告的结果测量上均有中度到非常强的证据表明无差异。这些结果表明，在与运动相关的脑震荡后 6 个月内，特定于疾病的 HRQoL 恢复到非脑震荡个体的水平。
