Lin Yong-Peng, Lin Rui, Chen Song, Rao Si-Yuan, Zhao Shuai, Wen Tao, Wang Hong-Shen, Hu Wei-Xiong, Liu Bing-Xin, Li Xin-Yi, Li Yong-Jin, Chen Bo-Lai
Guangzhou University of Chinese Medicine, Guangzhou, China.
Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Ann Transl Med. 2021 Jun;9(12):977. doi: 10.21037/atm-21-2181.
The aim of the present study was to evaluate the curative effect and safety of thoracic full-endoscopic unilateral laminotomy with bilateral decompression (TE-ULBD) for treating ossification of the ligamentum flavum (OLF) with myelopathy.
Between January 2015 and December 2018, 23 consecutive patients with symptomatic thoracic OLF were treated with TE-ULBD. Of these, 21 (13 women and 8 men, aged 49-75 years) were included in the study and followed up for a minimum of 1 year. The mean blood loss was 15.48 mL (10-30 mL), operative duration was 78.86 min (55-115 min), and hospitalization was 5.05 days (3-15 days). The Japanese Orthopaedic Association (JOA) was used to evaluate spinal cord function, and the curative effect was defined by the JOA improvement rate. The area of OLF (AOLF), the maximum spinal cord compression (MSCC), and the area of spinal cord (ASC) were used to evaluate OLF clearance and spinal cord decompression status.
At the final follow up,the JOA score was 8.33 points (5-11 points), which was a significant improvement from the preoperative 5.33 points (3-9 points, P<0.01). The excellent and good rate was 76.19% (16/21). The average preoperative AOLF and AOLF ratio were 85.27±23.66 mm and 57.86%±11.86%, respectively, and the postoperative AOLF and AOLF ratio were 16.27±11.75 mm and 8.13%±5.38%, respectively. The MSCC increased from 27.99%±13.51% preoperatively to 48.02%±6.66% postoperatively. The ASC was 42.90±10.60 mm preoperatively and 64.54±21.36 mm postoperatively. There were statistically significant differences in all parameters preoperatively and postoperatively (P<0.01). One case had postoperative hematoma, and the symptoms gradually eased after 3 weeks of conservative treatment. There were no other complications. No recurrence of OLF was detected during the follow-up period.
TE-ULBD is safe and effective for thoracic OLF with the advantages of reduced trauma and bleeding, and faster recovery.
本研究旨在评估胸腔镜下全内镜单侧椎板切开双侧减压术(TE-ULBD)治疗黄韧带骨化(OLF)伴脊髓病的疗效和安全性。
2015年1月至2018年12月,连续23例有症状的胸椎OLF患者接受TE-ULBD治疗。其中21例(13例女性,8例男性,年龄49 - 75岁)纳入研究并至少随访1年。平均失血量为15.48 mL(10 - 30 mL),手术时间为78.86分钟(55 - 115分钟),住院时间为5.05天(3 - 15天)。采用日本骨科协会(JOA)评分评估脊髓功能,疗效以JOA改善率定义。OLF面积(AOLF)、脊髓最大受压面积(MSCC)和脊髓面积(ASC)用于评估OLF清除情况和脊髓减压状态。
末次随访时,JOA评分为8.33分(5 - 11分),较术前5.33分(3 - 9分)有显著改善(P<0.01)。优良率为76.19%(16/21)。术前平均AOLF和AOLF比值分别为85.27±23.66 mm和57.86%±11.86%,术后分别为16.27±11.75 mm和8.13%±5.38%。MSCC从术前的27.99%±13.51%增加到术后的48.02%±6.66%。术前ASC为42.90±10.60 mm,术后为64.54±21.36 mm。所有参数术前与术后比较差异均有统计学意义(P<0.01)。1例患者术后出现血肿,经3周保守治疗后症状逐渐缓解。无其他并发症。随访期间未检测到OLF复发。
TE-ULBD治疗胸椎OLF安全有效,具有创伤小、出血少、恢复快的优点。