飞秒激光制瓣准分子原位角膜磨镶术前后角膜高阶像差的相关因素

Factors associated with corneal high-order aberrations before and after femtosecond laser-assisted keratomileusis.

作者信息

Zeng Jun, Lan Gongpu, Zhu Min, Sun Kai, Shi Qun, Ma Guoqing, Liu Quan

机构信息

Department of Ophthalmology, The First People's Hospital of Foshan, Foshan, China.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, China.

出版信息

Ann Transl Med. 2021 Jun;9(12):989. doi: 10.21037/atm-21-2367.

DOI:10.21037/atm-21-2367

PMID:34277789

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8267252/

Abstract

BACKGROUND

Corneal high-order aberrations (HOAs) are related to visual quality. However, the factors associated with corneal HOAs before and after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) have not yet been elucidated. The aim of this study is to observe the factors related to corneal HOAs before and after FS-LASIK.

METHODS

Prospective observational study was designed to measure corneal HOAs in 149 eyes of 75 patients before and 6 months after FS-LASIK. The relationship between spherical diopter and corneal parameters, including K1 and K2 (horizontal and vertical refractive power of the cornea, respectively), the aspheric characteristics of the cornea (Q), mean radius of the curvature of the cornea (Rm), and central corneal thickness (CCT), with corneal HOAs were analyzed.

RESULTS

The spherical diopter was correlated with trefoil at 30° before surgery and with vertical coma, four-order astigmatism at 0°, trefoil at 30°, spherical aberration, and six-order spherical aberration after surgery (P<0.05). CCT was correlated with vertical coma, four-order astigmatism at 0°, trefoil at 30°, and six-order spherical aberration after surgery (P<0.05). K1 was correlated with spherical aberration and six-order astigmatism at 0° before surgery (P<0.05). K2 was correlated with spherical aberration, six-order astigmatism at 45°, astigmatism at 0°, six-order astigmatism at 0° before surgery, and trefoil at 30° after surgery (P<0.05). Q was correlated with spherical aberration, six-order spherical aberration, and six-order astigmatism at 45° (P<0.05). Rm was correlated with six-order astigmatism at 0°, spherical aberration, six-order astigmatism at 45° before surgery, and astigmatism at 0° after surgery (P<0.05).

CONCLUSIONS

Corneal parameters and spherical diopter are related to the HOAs of the cornea before and after FS-LASIK.

摘要

背景

角膜高阶像差（HOAs）与视觉质量相关。然而，飞秒激光原位角膜磨镶术（FS-LASIK）前后与角膜HOAs相关的因素尚未阐明。本研究的目的是观察FS-LASIK前后与角膜HOAs相关的因素。

方法

设计前瞻性观察性研究，对75例患者的149只眼在FS-LASIK术前及术后6个月测量角膜HOAs。分析球镜度数与角膜参数之间的关系，这些角膜参数包括K1和K2（分别为角膜的水平和垂直屈光力）、角膜的非球面特性（Q）、角膜曲率平均半径（Rm）和中央角膜厚度（CCT）与角膜HOAs的关系。

结果

术前球镜度数与30°三叶形像差相关，术后与垂直彗差、0°四阶像散、30°三叶形像差、球差和六阶球差相关（P<0.05）。CCT与术后垂直彗差、0°四阶像散、30°三叶形像差和六阶球差相关（P<0.05）。术前K1与球差和0°六阶像散相关（P<0.05）。K2与球差、45°六阶像散、0°像散、术前0°六阶像散和术后30°三叶形像差相关（P<0.05）。Q与球差、六阶球差和45°六阶像散相关（P<0.05）。Rm与0°六阶像散、球差、术前45°六阶像散和术后0°像散相关（P<0.05）。