Baoding Yinghua Eye Hospital, Baoding, 071000, China.
Department of endocrinology, Affiliated Hospital of Hebei University, Baoding, 071000, China.
BMC Ophthalmol. 2020 Nov 26;20(1):465. doi: 10.1186/s12886-020-01727-z.
This study investigated the characteristics of corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea in adolescents with mild to moderate myopia.
A total of 183 patients with myopia (183 eyes) aged 8 to 18 years were enrolled in this study. The axial length (AL) of the eyes was measured by an IOL-Master, and corneal curvatures (K-values) and HOAs were measured by a Pentacam anterior segment diagnostic analyzer.
Results of this study showed that the anterior, posterior and total corneal horizontal coma Z were - 0.1249 ± 0.105 μm, 0.0009 ± 0.001 μm, and - 0.1331 ± 0.116 μm, respectively; the anterior, posterior and total corneal vertical coma Z were - 0.0212 ± 0.164 μm, 0.0003 ± 0.043 μm, and - 0.0216 ± 0.168 μm, respectively; and spherical aberration (SA) Z values were 0.2244 ± 0.091 μm, 0.1437 ± 0.029 um, and 0.1889 ± 0.090 μm, respectively. Total corneal Z was statistically correlated with posterior corneal astigmatism (Kb - Kb) (p = 0.038). Total corneal Z was correlated with anterior corneal astigmatism (Kf - Kf) (p = 0.027). Anterior, posterior, and total corneal Z were correlated with anterior and posterior corneal curvature (Kf, Kf, Kb, Kb) (p = 0.001). Posterior corneal Zb was also significantly correlated with AL.
In adolescents with mild to moderate myopia, the posterior corneal surface shape may play a compensatory role in the balance of corneal aberrations, and the posterior corneal SA tended to become less negative as the AL increased. The corneal coma may also play a compensatory role in posterior corneal surface astigmatism, which was valuable for the treatment for improving visual quality. This conclusion still needs to be verified.
本研究旨在探讨轻中度近视青少年角膜前表面、后表面和总角膜高阶像差(HOAs)的特征。
本研究共纳入 183 例(183 只眼)近视患者,年龄 8 至 18 岁。眼轴长度(AL)通过 IOL-Master 测量,角膜曲率(K 值)和 HOAs 通过 Pentacam 眼前节诊断分析仪测量。
本研究结果显示,角膜前、后表面水平彗差 Z 值分别为-0.1249±0.105μm、0.0009±0.001μm 和-0.1331±0.116μm;角膜前、后表面垂直彗差 Z 值分别为-0.0212±0.164μm、0.0003±0.043μm 和-0.0216±0.168μm;球差 Z 值分别为 0.2244±0.091μm、0.1437±0.029μm 和 0.1889±0.090μm。总角膜 Z 值与后角膜散光(Kb-Kb)呈统计学相关(p=0.038)。总角膜 Z 值与前角膜散光(Kf-Kf)相关(p=0.027)。前、后、总角膜 Z 值与前、后角膜曲率(Kf、Kf、Kb、Kb)相关(p=0.001)。后角膜 Zb 也与 AL 显著相关。
在轻中度近视的青少年中,后角膜表面形状可能在角膜像差平衡中起补偿作用,随着 AL 的增加,后角膜球差趋于变得更负。角膜彗差在后角膜表面散光中也可能起补偿作用,这对于改善视觉质量的治疗有价值。这一结论仍有待验证。