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青少年轻中度近视眼角膜高阶像差特征。

Characteristics of corneal high-order aberrations in adolescents with mild to moderate myopia.

机构信息

Baoding Yinghua Eye Hospital, Baoding, 071000, China.

Department of endocrinology, Affiliated Hospital of Hebei University, Baoding, 071000, China.

出版信息

BMC Ophthalmol. 2020 Nov 26;20(1):465. doi: 10.1186/s12886-020-01727-z.

Abstract

BACKGROUND

This study investigated the characteristics of corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea in adolescents with mild to moderate myopia.

METHODS

A total of 183 patients with myopia (183 eyes) aged 8 to 18 years were enrolled in this study. The axial length (AL) of the eyes was measured by an IOL-Master, and corneal curvatures (K-values) and HOAs were measured by a Pentacam anterior segment diagnostic analyzer.

RESULTS

Results of this study showed that the anterior, posterior and total corneal horizontal coma Z were - 0.1249 ± 0.105 μm, 0.0009 ± 0.001 μm, and - 0.1331 ± 0.116 μm, respectively; the anterior, posterior and total corneal vertical coma Z were - 0.0212 ± 0.164 μm, 0.0003 ± 0.043 μm, and - 0.0216 ± 0.168 μm, respectively; and spherical aberration (SA) Z values were 0.2244 ± 0.091 μm, 0.1437 ± 0.029 um, and 0.1889 ± 0.090 μm, respectively. Total corneal Z was statistically correlated with posterior corneal astigmatism (Kb - Kb) (p = 0.038). Total corneal Z was correlated with anterior corneal astigmatism (Kf - Kf) (p = 0.027). Anterior, posterior, and total corneal Z were correlated with anterior and posterior corneal curvature (Kf, Kf, Kb, Kb) (p = 0.001). Posterior corneal Zb was also significantly correlated with AL.

CONCLUSIONS

In adolescents with mild to moderate myopia, the posterior corneal surface shape may play a compensatory role in the balance of corneal aberrations, and the posterior corneal SA tended to become less negative as the AL increased. The corneal coma may also play a compensatory role in posterior corneal surface astigmatism, which was valuable for the treatment for improving visual quality. This conclusion still needs to be verified.

摘要

背景

本研究旨在探讨轻中度近视青少年角膜前表面、后表面和总角膜高阶像差(HOAs)的特征。

方法

本研究共纳入 183 例(183 只眼)近视患者,年龄 8 至 18 岁。眼轴长度(AL)通过 IOL-Master 测量,角膜曲率(K 值)和 HOAs 通过 Pentacam 眼前节诊断分析仪测量。

结果

本研究结果显示,角膜前、后表面水平彗差 Z 值分别为-0.1249±0.105μm、0.0009±0.001μm 和-0.1331±0.116μm;角膜前、后表面垂直彗差 Z 值分别为-0.0212±0.164μm、0.0003±0.043μm 和-0.0216±0.168μm;球差 Z 值分别为 0.2244±0.091μm、0.1437±0.029μm 和 0.1889±0.090μm。总角膜 Z 值与后角膜散光(Kb-Kb)呈统计学相关(p=0.038)。总角膜 Z 值与前角膜散光(Kf-Kf)相关(p=0.027)。前、后、总角膜 Z 值与前、后角膜曲率(Kf、Kf、Kb、Kb)相关(p=0.001)。后角膜 Zb 也与 AL 显著相关。

结论

在轻中度近视的青少年中,后角膜表面形状可能在角膜像差平衡中起补偿作用,随着 AL 的增加,后角膜球差趋于变得更负。角膜彗差在后角膜表面散光中也可能起补偿作用,这对于改善视觉质量的治疗有价值。这一结论仍有待验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7a/7690177/f6c789ae06ff/12886_2020_1727_Fig1_HTML.jpg

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