复发性口腔溃疡中的人类白细胞抗原：反对与白塞病存在共同疾病谱的证据。
HLA antigens in recurrent oral ulceration: evidence against a common disease spectrum with Behçet's syndrome.
作者信息
Ozbakir F, Yazici H, Mat C, Tüzün Y, Yurdakul S, Yilmazer S
机构信息
Department of Medicine, University of Istanbul, Turkey.
出版信息
Clin Exp Rheumatol. 1987 Jul-Sep;5(3):263-5.
PMID:3427840
Abstract
Among 50 patients with recurrent oral ulceration (ROU) the prevalence of HLA B5 was not increased as was the case among 50 patients with Behçet's Syndrome (BS) compared to 52 healthy controls. On the other hand, HLA DR4 was present in 16 of 30 (53%) patients with ROU whereas the same allele was present in 16% of BS patients and 22% of the healthy controls. These findings suggest that ROU and BS are not in the same disease spectrum.
摘要
在50例复发性口腔溃疡（ROU）患者中，与52例健康对照相比，HLA B5的患病率并未像在50例白塞病（BS）患者中那样升高。另一方面，30例ROU患者中有16例（53%）存在HLA DR4，而在BS患者中该等位基因的存在率为16%，在健康对照中为22%。这些发现表明，ROU和BS不属于同一疾病谱。
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