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初级保健提供者管理儿童特应性皮炎:系统评价。

Management of Pediatric Atopic Dermatitis by Primary Care Providers: A Systematic Review.

机构信息

New York University Grossman School of Medicine (TK Young, AM Kolla, and J Nicholson), New York, NY.

Department of Pediatrics, New York University Grossman School of Medicine (AF Glick, HS Yin, JJ Velazquez, and VS Oza), New York, NY.

出版信息

Acad Pediatr. 2021 Nov-Dec;21(8):1318-1327. doi: 10.1016/j.acap.2021.07.008. Epub 2021 Jul 17.

Abstract

BACKGROUND

Primary care providers (PCPs), including pediatricians and general practitioners, are often the first to see children with eczema/atopic dermatitis (AD). Little is known about management of pediatric AD by PCPs and adherence to national guidelines.

OBJECTIVE

To review existing literature examining management components of pediatric AD (topical corticosteroids [TCS], topical calcineurin inhibitors [TCIs], antihistamines, bathing, emollients, and diet) by PCPs.

DATA SOURCES

PubMed/Medline and Embase.

STUDY ELIGIBILITY CRITERIA

English-language articles dated 2015 to 2020 reporting outcomes addressing management of pediatric AD by PCPs.

STUDY APPRAISAL AND SYNTHESIS METHODS

Two authors independently screened titles/abstracts, reviewed full-text articles, extracted relevant data, and evaluated study quality. Disagreements were resolved by a third author.

RESULTS

Twenty articles were included. Surveys and national database analyses were the most common methodologies (n = 7 each). PCPs commonly prescribed TCS but had a preference for low-potency agents, overprescribed nonsedating antihistamines, and avoided TCIs. PCPs commonly recommended emollients, although this was not universal. Data characterizing nonmedication management were limited.

LIMITATIONS

Most studies did not examine individual patient encounters, but rather relied on providers reporting their general behaviors. Provider behavior may vary based on country of practice.

CONCLUSIONS AND IMPLICATIONS OF KEY FINDINGS

Knowledge and management gaps exist among PCPs in treating pediatric AD in key areas including knowledge of TCS safety profiles and prescribing of TCIs. The current literature is largely limited to small studies that evaluate prescribing behaviors with limited data characterizing nonmedication management, highlighting the need for future research in this area.

摘要

背景

初级保健提供者(PCP),包括儿科医生和全科医生,通常是首次接诊患有湿疹/特应性皮炎(AD)的儿童。关于 PCP 对儿科 AD 的管理以及对国家指南的依从性,人们知之甚少。

目的

回顾现有的文献,以审查 PCP 对儿科 AD(局部皮质类固醇[TCS]、局部钙调神经磷酸酶抑制剂[TCIs]、抗组胺药、沐浴、保湿剂和饮食)管理的各个组成部分。

数据来源

PubMed/Medline 和 Embase。

研究入选标准

发表于 2015 年至 2020 年的英语文章,报告了 PCP 管理儿科 AD 的结果。

研究评估和综合方法

两名作者独立筛选标题/摘要、审阅全文文章、提取相关数据,并评估研究质量。分歧由第三位作者解决。

结果

共纳入 20 篇文章。调查和国家数据库分析是最常见的方法(各 7 篇)。PCP 通常开处方 TCS,但更喜欢低效能制剂,过度开处方非镇静性抗组胺药,避免 TCIs。PCP 通常推荐使用保湿剂,尽管并非普遍如此。关于非药物治疗管理的数据有限。

局限性

大多数研究没有检查个体患者的就诊情况,而是依赖于提供者报告他们的一般行为。提供者的行为可能因所在国家/地区的实践而异。

结论和关键发现的意义

在治疗儿科 AD 的关键领域,包括 TCS 安全性概况的知识和 TCI 的处方,PCP 存在知识和管理差距。目前的文献主要局限于评估处方行为的小型研究,有限的数据描述非药物治疗管理,这突出了该领域未来研究的必要性。

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