Division of Mental Health & Wellbeing, Warwick Medical School, University of Warwick.
Coventry and Warwickshire Partnership Trust, Coventry, UK.
Curr Opin Psychiatry. 2021 Sep 1;34(5):460-466. doi: 10.1097/YCO.0000000000000726.
Assessing recent evidence on psychosocial interventions for people with first episode psychosis (FEP).
Family interventions (FI) reduce relapse rates, whilst cognitive behavioural therapy (CBT) shows a moderate effect in improving positive psychotic symptoms. Vocational interventions (VI) appear to be worthy of implementation within early intervention for psychosis (EIP) teams, but it is still unclear what is the most cost-effective strategy for their delivery. Promising interventions, which need more careful evaluation, focus on substance misuse, physical health comorbidities, improvement of social participation, peer support and the potential of new technologies.
The first five years after the onset of psychotic symptoms are a 'critical period' in which psychosocial interventions can be particularly influential in determining prognosis. Traditional EIP interventions have different effectiveness profiles, i.e., FI reduce relapse rates, CBT has a moderate effectiveness on overall and positive symptoms and VI can improve educational and employment-related functioning. Newer interventions show promise on important targets for FEP treatment but require higher-quality evaluations. Decisions on which interventions to implement within EIP teams should be informed by high-quality evidence, but difficult choices will have to be made based on costs, professionals and technologies available, and local priorities.
评估首发精神病患者(FEP)心理社会干预的最新证据。
家庭干预(FI)可降低复发率,而认知行为疗法(CBT)在改善阳性精神病症状方面显示出中等效果。职业干预(VI)似乎值得在精神病早期干预(EIP)团队中实施,但仍不清楚其实施的最具成本效益的策略是什么。有前途的干预措施,需要更仔细的评估,侧重于药物滥用、身体健康合并症、社会参与、同伴支持以及新技术的潜力。
精神病症状出现后的头五年是“关键时期”,在此期间,心理社会干预可以特别影响预后。传统的 EIP 干预措施具有不同的有效性特征,即 FI 降低复发率,CBT 对整体和阳性症状有中等效果,VI 可改善教育和与就业相关的功能。新的干预措施在 FEP 治疗的重要目标上显示出前景,但需要进行更高质量的评估。在 EIP 团队中实施哪些干预措施的决策应基于高质量的证据,但必须根据成本、专业人员和可用技术以及当地重点做出艰难的选择。