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以色列智障儿童中多发发涡的临床意义及其与异常皮纹和畸形特征的关联。

The clinical significance of multiple hair whorls and their association with unusual dermatoglyphics and dysmorphic features in mentally retarded Israeli children.

作者信息

Tirosh E, Jaffe M, Dar H

机构信息

Hannah Khoushy Child Development Center, Haifa Medical Center (Rothschild), Israel.

出版信息

Eur J Pediatr. 1987 Nov;146(6):568-70. doi: 10.1007/BF02467355.

DOI:10.1007/BF02467355
PMID:3428291
Abstract

The prevalence of multiple hair whorls in a group of mentally retarded patients was 8% as opposed to 3.6% in a group of healthy children. A statistically significant relationship was demonstrated between mental retardation, multiple hair whorls, more than two dysmorphic features, and unusual dermatoglyphics. The results confirm the importance of multiple hair whorls as a genuine dysmorphic feature. The significance of these markers in the evaluation of mentally retarded subjects is discussed, with special reference to the timing of the fetal insult.

摘要

一组智力迟钝患者中多发发旋的患病率为8%,而一组健康儿童中的患病率为3.6%。研究表明,智力迟钝、多发发旋、两种以上畸形特征和异常皮纹之间存在统计学上的显著关系。结果证实了多发发旋作为一种真正的畸形特征的重要性。本文讨论了这些标志物在评估智力迟钝受试者中的意义,并特别提及了胎儿受损伤的时间。

相似文献

1
The clinical significance of multiple hair whorls and their association with unusual dermatoglyphics and dysmorphic features in mentally retarded Israeli children.以色列智障儿童中多发发涡的临床意义及其与异常皮纹和畸形特征的关联。
Eur J Pediatr. 1987 Nov;146(6):568-70. doi: 10.1007/BF02467355.
2
Dermatoglyphic and palmar-crease alterations as indicators of early intra-uterine insult in mental retardation.皮纹和掌纹改变作为智力低下早期宫内损伤的指标。
Dev Med Child Neurol. 1983 Feb;25(1):53-9. doi: 10.1111/j.1469-8749.1983.tb13721.x.
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Mental retardation with facial abnormalities, broad thumbs and toes and unusual dermatoglyphics.智力发育迟缓伴面部异常、拇指和脚趾宽大及特殊皮纹。
Dev Med Child Neurol. 1967 Oct;9(5):588-93. doi: 10.1111/j.1469-8749.1967.tb02329.x.
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Kabuki make-up syndrome: a syndrome of mental retardation, unusual facies, large and protruding ears, and postnatal growth deficiency.
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A new craniodigital syndrome with mental retardation.一种伴有智力发育迟缓的新型颅指综合征。
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[Trisomy of the chromosome 18 in a mentally retarded child with hyperphenylalaninemia].[一名患有高苯丙氨酸血症的智力发育迟缓儿童的18号染色体三体]
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本文引用的文献

1
CONGENITAL ANOMALIES ASSOCIATED WITH IDIOPATHIC MENTAL RETARDATION.
J Pediatr. 1964 Aug;65:189-96. doi: 10.1016/s0022-3476(64)80519-9.
2
CONGENITAL ANOMALIES IN THE NEWBORN INFANT, INCLUDING MINOR VARIATIONS. A STUDY OF 4,412 BABIES BY SURFACE EXAMINATION FOR ANOMALIES AND BUCCAL SMEAR FOR SEX CHROMATIN.新生儿先天性异常,包括轻微变异。对4412名婴儿进行体表异常检查和口腔涂片性染色质检查的研究。
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Minor craniofacial anomalies in children. Comparative study of a qualitative and quantitative evaluation.儿童轻微颅面异常。定性与定量评估的比较研究。
Eur J Pediatr. 1980 May;133(3):243-50. doi: 10.1007/BF00496084.
4
Dermatoglyphic and palmar-crease alterations as indicators of early intra-uterine insult in mental retardation.皮纹和掌纹改变作为智力低下早期宫内损伤的指标。
Dev Med Child Neurol. 1983 Feb;25(1):53-9. doi: 10.1111/j.1469-8749.1983.tb13721.x.
5
Unusual dermatoglyphic findings associated with rubella embryopathy.与风疹胚胎病相关的异常皮纹学表现。
N Engl J Med. 1966 Jan 20;274(3):148-50. doi: 10.1056/NEJM196601202740307.
6
Minor physical anomalies and academic performance in young school-children.小学儿童的轻微身体异常与学业成绩
Dev Med Child Neurol. 1973 Apr;15(2):131-5. doi: 10.1111/j.1469-8749.1973.tb15152.x.
7
Scalp hair patterning as a clue to early fetal brain development.头皮毛发形态作为早期胎儿大脑发育的线索。
J Pediatr. 1973 Sep;83(3):374-80. doi: 10.1016/s0022-3476(73)80258-6.
8
Minor physical anomalies and behavior in preschool children.学龄前儿童的轻微身体异常与行为
Child Dev. 1968 Jun;39(2):391-400.
9
Hair crown patterns of human newborns. Studies on parietal hair whorl locations and their directions.人类新生儿的头冠毛发模式。关于顶骨发旋位置及其方向的研究。
Clin Pediatr (Phila). 1975 Nov;14(11):1045-9. doi: 10.1177/000992287501401111.
10
Routine analysis of dermatoglyphics and palmar creases in children with developmental disorders.发育障碍儿童皮纹和掌纹的常规分析。
Dev Med Child Neurol. 1978 Dec;20(6):735-7. doi: 10.1111/j.1469-8749.1978.tb15304.x.