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一名患有维斯科特-奥尔德里奇综合征的患者中,肾上腺皮质功能不全与爱泼斯坦-巴尔病毒感染相关。

Adrenocortical insufficiency associated with Epstein-Barr virus infection in a patient with the Wiskott-Aldrich syndrome.

作者信息

Hertel N T, Jacobsen B B, Pedersen F K, Heilmann C

机构信息

University Clinic of Pediatrics, Department G, Rigshospitalet, Copenhagen, Denmark.

出版信息

Eur J Pediatr. 1987 Nov;146(6):603-4. doi: 10.1007/BF02467365.

Abstract

A 10-year-old boy with the Wiskott-Aldrich syndrome developed adrenocortical insufficiency including typical clinical findings, low s-Na, high s-K, high p-ACTH (640 ng/l), low p-aldosterone (33-39 pmol/l), high p-renin (2300-4200 mIU/l) as well as an abnormal response to an ACTH-stimulation test. The adrenocortical insufficiency developed concomitantly with the occurrence of infectious mononucleosis diagnosed clinically and serologically. Adrenalitis caused by Epstein-Barr virus is suggested as the causative factor.

摘要

一名患有威斯科特-奥尔德里奇综合征的10岁男孩出现肾上腺皮质功能不全,包括典型的临床症状、低血钠、高血钾、高血浆促肾上腺皮质激素(640 ng/l)、低血浆醛固酮(33 - 39 pmol/l)、高血浆肾素(2300 - 4200 mIU/l)以及促肾上腺皮质激素刺激试验反应异常。肾上腺皮质功能不全与临床和血清学诊断的传染性单核细胞增多症同时出现。提示由爱泼斯坦-巴尔病毒引起的肾上腺炎为致病因素。

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