Assistant Professor, Pediatric Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, Rishikesh, India.
Assistant Professor, Department of Neurology, King George Medical University, Lucknow, India.
Trop Doct. 2021 Oct;51(4):518-522. doi: 10.1177/00494755211032095. Epub 2021 Jul 20.
Seizures triggered by skin application, inhalation or ingestion of over-the-counter medications containing eucalyptus oil are known. We report five children who suffered likewise. We made a systematic search for all reported cases and performed a pooled analysis to provide a comprehensive estimate of the type of seizures, their management and outcome. In 110 cases (49 children), inhalational use was the most predominant, generalised tonic-clonic (the commonest semiology) and levetiracetam was the most common anti-convulsant treatment used. Most cases had an uneventful recovery. Adults were less likely to have prolonged and multiple seizures, requiring intensive care or mechanical ventilation.
已知皮肤涂抹、吸入或摄入含有桉树油的非处方药物会引发癫痫。我们报告了五例类似的儿童病例。我们系统地搜索了所有报告的病例，并进行了汇总分析，以提供对癫痫发作类型、治疗和结果的全面估计。在 110 例（49 例儿童）中，吸入是最主要的使用方式，全身性强直阵挛（最常见的症状），左乙拉西坦是最常用的抗癫痫药物。大多数病例恢复良好。成人不太可能出现持续时间长和多次发作，需要重症监护或机械通气。
