寻找死后代谢组学标准化：等待戈多——死后间隔时间在法医代谢组学中的重要性。
Looking for Post-Mortem Metabolomic Standardization: Waiting for Godot-The Importance of Post-Mortem Interval in Forensic Metabolomics.
机构信息
Department of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, 09042, Italy.
出版信息
Chem Res Toxicol. 2021 Sep 20;34(9):1946-1947. doi: 10.1021/acs.chemrestox.1c00211. Epub 2021 Jul 20.
Abstract
A growing body of evidence suggests that the post-mortem interval exerts a strong effect on the metabolome, independently of the biological matrix or the cause of death. A sound and shared approach in standardization is mandatory.
摘要
越来越多的证据表明，死后间隔时间对代谢组有很强的影响，而与生物基质或死亡原因无关。标准化的健全和共享方法是强制性的。
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