Department of Orthopedic Surgery, Balgrist University Hospital, University of Zurich, Switzerland.
Department of Radiology, Balgrist University Hospital, University of Zurich, Switzerland.
Spine J. 2022 Jan;22(1):75-83. doi: 10.1016/j.spinee.2021.07.009. Epub 2021 Jul 17.
Early postoperative MR images are frequently necessary after spine surgery. The appearance of commonly used adjunct hemostatic agents and dural sealants in MR images has not been systematically evaluated.
The purpose of this experimental study was to systematically analyze and describe the characteristics of the most commonly applied hemostatic agents and dural sealants in spine surgery on early postoperative MR images.
Cadaver Study METHODS: Four commonly applied dural sealants (Duraseal, Bioglue, Tachosil, Tisseel) and five commonly used hemostatic agents (Surgiflo, Bonewax, , Spongostan, Gelfoam, Avitene) were investigated. The experimental setting involved a human cadaver where a standard left-sided laminotomy was performed on nine levels of the thoracolumbar spine, and the materials were separately applied and mixed with fresh blood or water for hemostatic and dural sealants, respectively. The cadaver model was scanned at a 3 Tesla MRI and the imaging findings for all materials were compared to the surrounding tissue and systematically reported.
All investigated dural sealants and hemostatic agents were distinguishable from the surrounding tissue on MR images with different appearances on the MR sequences. A detailed atlas for the identification of the materials in postoperative spine MRI was established.
Commonly used hemostatic agents and dural sealants can be successfully identified on early postoperative spine MRI.
Knowledge about MRI appearances of commonly used adjunct surgical materials helps in interpretation of postoperative imaging and supports clinical decision making.
脊柱手术后通常需要早期进行术后磁共振成像(MRI)检查。然而,目前尚未系统评估常用辅助止血剂和硬脑膜密封剂在 MRI 图像中的表现。
本实验研究旨在系统分析和描述脊柱外科中最常用的止血剂和硬脑膜密封剂在术后早期 MRI 图像中的特征。
尸体研究
研究纳入了 4 种常用硬脑膜密封剂(Duraseal、Bioglue、Tachosil、Tisseel)和 5 种常用止血剂(Surgiflo、Bonewax、Spongostan、Gelfoam、Avitene)。在人体尸体标本中进行实验,对 9 个胸腰椎节段进行标准左侧椎板切除术,分别单独应用并将其与新鲜血液或水混合以模拟止血和硬脑膜密封剂的效果。使用 3T MRI 对尸体模型进行扫描,对所有材料的成像结果与周围组织进行比较,并进行系统报告。
所有研究的硬脑膜密封剂和止血剂在 MRI 图像上均能与周围组织区分开来,在不同的 MRI 序列上呈现不同的表现。建立了术后脊柱 MRI 中识别这些材料的详细图谱。
在术后早期脊柱 MRI 上可以成功识别常用的止血剂和硬脑膜密封剂。
了解术后常用辅助手术材料在 MRI 上的表现有助于解读术后影像学结果,并为临床决策提供支持。