From the Department of Radiology, Fukushima Medical University, Fukushima, Japan.
Clin Nucl Med. 2022 Feb 1;47(2):e149-e151. doi: 10.1097/RLU.0000000000003833.
Hypertrophic pachymeningitis is a rare inflammatory process characterized by thickening of the dura mater that can be idiopathic or secondary to a variety of conditions such as ANCA-related vasculitis, IgG4-related disease, Sjögren syndrome, rheumatoid arthritis, sarcoidosis, and infections. It can cause various neurological alterations such as headache, cranial nerve disorder, cerebellar disorder, sensory impairment, and weakness. Brain MRI is useful for imaging diagnosis of hypertrophic pachymeningitis, showing focal thickening and enhancement of the dura mater. Here we report 4 cases of idiopathic hypertrophic pachymeningitis where 67Ga clearly accumulated in the dura mater.
肥厚性脑脊膜炎是一种罕见的炎症过程,其特征为硬脑膜增厚,可为特发性,也可为多种疾病所引起,如抗中性粒细胞胞浆抗体相关性血管炎、IgG4 相关疾病、干燥综合征、类风湿关节炎、结节病和感染等。它可引起各种神经学改变,如头痛、颅神经障碍、小脑障碍、感觉障碍和无力。脑 MRI 对肥厚性脑脊膜炎的影像学诊断很有帮助,表现为硬脑膜局灶性增厚和强化。本文报告 4 例特发性肥厚性脑脊膜炎,67Ga 在硬脑膜中明显聚集。