Kaczmarczyk Michał S, Jurkiewicz Dariusz, Niemczyk Stanisław, Rymarz Aleksandra
Department of Otolaryngology and Laryngological Oncology with Clinical Department of Craniofacial Surgery, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-349 Warsaw, Poland.
Department of Internal Diseases, Nephrology and Dialysis, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-349 Warsaw, Poland.
J Clin Med. 2024 Jul 23;13(15):4298. doi: 10.3390/jcm13154298.
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of vasculitis sharing a common pathophysiology, which affects small and medium blood vessels. There are three categories of AAV: granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA). As a systemic disease, AAV can affect basically every organ. The goal of this publication is to sum up and underline the problem of the aural manifestation of AAV; it details the definition of Otitis Media with Antineutrophil Cytoplasmic Antibody Associated Vasculitis (OMAAV) and allows for a better understanding of the specific tasks of medical professionals taking part in the diagnostic and therapeutic process. Among others, this publication is directed to otolaryngologists who may encounter patients with AAV and often are the first specialists who see patients with early symptoms of AAV. This publication presents brief characteristics of AAV, descriptions of aural manifestations and symptoms, differential diagnosis, and both pharmacological and surgical treatment options, based on current recommendations and information found in the literature and clinical databases.
抗中性粒细胞胞浆抗体（ANCA）相关性血管炎（AAV）是一组具有共同病理生理学特征的血管炎，可累及中小血管。AAV有三类：肉芽肿性多血管炎（GPA）、显微镜下多血管炎（MPA）和嗜酸性肉芽肿性多血管炎（EGPA）。作为一种全身性疾病，AAV基本上可累及每个器官。本出版物的目的是总结并强调AAV耳部表现的问题；详细阐述抗中性粒细胞胞浆抗体相关性血管炎伴中耳炎（OMAAV）的定义，以便更好地理解参与诊断和治疗过程的医学专业人员的具体任务。此外，本出版物面向可能遇到AAV患者的耳鼻喉科医生，他们通常是最早见到有AAV早期症状患者的专科医生。本出版物根据文献和临床数据库中的当前建议和信息，介绍了AAV的简要特征、耳部表现和症状描述、鉴别诊断以及药物和手术治疗方案。
