Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Izmir Democracy University, İzmir, Turkey.
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Turkey.
Turk J Med Sci. 2021 Oct;51(5):2621-2630. doi: 10.3906/sag-2102-55. Epub 2021 Oct 21.
To detect the extent to which physical impairments are observed in patients with lung cancer awaiting lung surgery, exercise capacity, muscle strength, physical activity, dyspnea, and quality of life (QOL) were objectively compared between the patients and healthy individuals in current study.
Patients with lung cancer (n = 26) and healthy individuals (n = 21) were included. Exercise capacity, respiratory (maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP)) and quadriceps femoris muscle strength, physical activity, dyspnea and QOL were evaluated using 6-min walk test (6-MWT), a mouth pressure device, a hand-held dynamometer, a metabolic holter device, Modified Medical Research Council dyspnea scale and European Organization for Research and Treatment of Cancer QOL Questionnaire C30 version 3.0, respectively.
The 6-MWT distance (mean difference: 78.97 m), percentages of predicted MIP and MEP values, physical activity parameters (energy expenditures, physical activity duration, average metabolic equivalent and number of steps) and QOL subscales scores (functional, social function and global health status) were significantly lower in the patients than healthy individuals (p < 0.05). Dyspnea perception and other QOL subscales scores (symptom and fatigue) were significantly higher in patients than healthy individuals (p < 0.05). No significant difference was prevalent in quadriceps femoris muscle strength (p > 0.05). Sixteen (66.7%) patients were sedentary.
Severe reductions in exercise capacity, respiratory muscle strength, and physical activity level, poorer QOL and evident dyspnea exist in preoperative patients with lung cancer. Therefore, patients should be included in early protective rehabilitation program including aerobic exercise, respiratory muscle training and physical activity counseling before lung surgery.
为了检测肺癌患者在接受肺手术前的身体损伤程度，本研究客观比较了患者与健康个体之间的运动能力、肌肉力量、身体活动、呼吸困难和生活质量（QOL）。
纳入了 26 例肺癌患者和 21 例健康个体。使用 6 分钟步行测试（6-MWT）、口腔压力仪、手持测力计、代谢监测仪、改良医学研究委员会呼吸困难量表和欧洲癌症研究与治疗组织生活质量问卷 C30 版本 3.0 分别评估了运动能力（6-MWT 距离、预测最大吸气压力和最大呼气压力的百分比）、呼吸（最大吸气压力和最大呼气压力）和股四头肌力量、身体活动、呼吸困难和生活质量。
与健康个体相比，患者的 6-MWT 距离（平均差异：78.97m）、预测最大吸气压力和最大呼气压力值的百分比、身体活动参数（能量消耗、身体活动持续时间、平均代谢当量和步数）和生活质量子量表评分（功能、社会功能和总体健康状况）显著降低（p<0.05）。患者的呼吸困难感知和其他生活质量子量表评分（症状和疲劳）显著高于健康个体（p<0.05）。股四头肌力量无显著差异（p>0.05）。16 例（66.7%）患者为久坐者。
术前肺癌患者的运动能力、呼吸肌力量和身体活动水平显著降低，生活质量较差，呼吸困难明显。因此，患者应在肺手术前纳入包括有氧运动、呼吸肌训练和身体活动咨询在内的早期保护康复计划。
