Department of Adult and Development Age Human Pathology 'Gaetano Barresi', Unit of Otorhinolaryngology, Universita degli Studi di Messina, Messina, Italy
University of Messina, Messina, Sicilia, Italy.
BMJ Case Rep. 2021 Jul 20;14(7):e241460. doi: 10.1136/bcr-2020-241460.
Lymphoepithelial carcinoma (LEC) is an entity mostly frequent in the nasopharynx, which represents 40% of all neoplasms. The incidence's not exclusive of a geographic area; however, it has an endemic distribution in Southeast Asia and Eskimos. LEC is not exclusive of the nasopharynx, has also been reported in other anatomical areas, such as the sinonasal tract, nasolacrimal duct, oral cavity, oropharynx, salivary glands, thymus, hypopharynx, oesophagus, stomach, trachea, lung and others. Non-nasopharyngeal and nasopharyngeal LEC have the same microscopic features, but the nasopharyngeal is more likely associated with Epstein-Barr virus. LEC has been approved by the WHO. LEC located in the larynx is quite rare and worthy of attention for its implication in the treatment and prognosis. We present a case of LEC treated in our ENT department in a middle-aged man.
淋巴上皮癌(LEC)是一种主要发生于鼻咽部的肿瘤,约占所有肿瘤的 40%。其发病率不限于某一地理区域;然而,它在东南亚和爱斯基摩人中具有地方性分布。LEC 不仅限于鼻咽部,也有报道发生于其他解剖部位,如鼻-鼻窦、鼻泪管、口腔、口咽、唾液腺、胸腺、下咽、食管、胃、气管、肺等。非鼻咽部和鼻咽部的 LEC 具有相同的显微镜特征,但鼻咽部更可能与 Epstein-Barr 病毒相关。WHO 已批准 LEC。位于喉部的 LEC 非常罕见,因其对治疗和预后的影响而值得关注。我们报告了一例在我院耳鼻喉科治疗的 LEC 患者,为中年男性。