Alqahtani Abdulhadi M, Almazrou Saja H, Alalweet Randah M, Almalki Ziyad S, Alqahtani Basmah F, AlGhamdi Saleh
Research Center, Clinical Research Department, King Fahad Medical City, Riyadh City, Saudi Arabia.
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Int J Gen Med. 2021 Jul 13;14:3405-3413. doi: 10.2147/IJGM.S318753. eCollection 2021.
We aimed to evaluate the impact of the COVID-19 pandemic on the knowledge and attitudes of patients among the Saudi population toward participating in clinical trials.
We conducted a descriptive, cross-sectional analysis using self-administered questionnaires for patients who attended the outpatient clinics at King Fahad Medical City and King Saud University Medical City in Riyadh, Saudi Arabia. The questionnaires included general questions about sociodemographic information, patient knowledge about clinical trials, and patient attitudes toward clinical trial participation. We used descriptive analysis to evaluate the impact of COVID-19 on patient knowledge and attitudes about clinical trials.
From November 2019 to October 2020, 822 responses were collected from participants in two medical cities and included in the analysis. Most of the study participants (81%) were younger than age 42 years. Our findings showed no difference between participants who participated in clinical trials before versus during the COVID-19 pandemic (P = 0.129).
The Saudi population knows about clinical trials, but they lack knowledge about the role of the ethics committee and about informed consent. Also, most of them do not have the experience of participating in a clinical trial. Still, they have moderately positive attitudes toward clinical trials.
我们旨在评估新冠疫情对沙特人群中患者参与临床试验的知识和态度的影响。
我们对沙特阿拉伯利雅得法赫德国王医疗城和沙特国王大学医疗城门诊就诊的患者采用自行填写问卷的方式进行了描述性横断面分析。问卷包括关于社会人口学信息的一般问题、患者对临床试验的了解以及患者对参与临床试验的态度。我们使用描述性分析来评估新冠疫情对患者关于临床试验的知识和态度的影响。
2019年11月至2020年10月，从两个医疗城的参与者中收集了822份回复并纳入分析。大多数研究参与者（81%）年龄小于42岁。我们的研究结果显示，在新冠疫情之前和期间参与临床试验的参与者之间没有差异（P = 0.129）。
沙特人群了解临床试验，但他们缺乏关于伦理委员会的作用和知情同意的知识。此外，他们中的大多数人没有参与过临床试验的经历。不过，他们对临床试验持适度积极的态度。
