Shi Weibin, Rudra Renuka, Vu To-Nhu, Gordin Yuri, Smith Ryan, Kunselman Allen R
Department of Physical Medicine and Rehabilitation, Penn State Health Milton S Hershey Medical Center, Penn State College of Medicine, Hershey, PA, USA.
Penn State Hershey Rehabilitation Hospital, Hummelstown, PA, USA.
J Pain Res. 2021 Jul 13;14:2113-2119. doi: 10.2147/JPR.S319622. eCollection 2021.
Sensory stimulation threshold (SST) has been used as a surrogate marker to target a nerve branch for radiofrequency (RF) denervation; however, the validity of SST as a prognostic marker is still under debate.
To assess whether lower SST values correlate with better outcomes of radiofrequency denervation for facetogenic low back pain.
Prospective cohort study.
Sixty-seven patients who underwent radiofrequency denervation for low back pain.
Correlations, between the average percentage of pain relief from diagnostic medial branch block (MBB) and RF denervation procedure outcome, and between SST and RF denervation procedure outcome, were analyzed using Spearman correlation coefficient ( ). Wilcoxon rank sum test was performed to assess whether magnitude and duration of pain relief following RF denervation differed by the levels of SST (<0.5 and ≥0.5) or pain relief (<80% and ≥80%) from diagnostic MBB.
There was a positive correlation between pain relief after diagnostic MBB and pain relief 2 weeks after denervation ( 0.31, 95% CI 0.08 to 0.51, p < 0.01), but not between pain relief after MBB and pain relief 6 months after denervation, nor pain relief duration after denervation. There was a negative correlation between SST and pain relief 6 months after denervation ( -0.41, 95% CI -0.59 to -0.18, p < 0.001). There was also a negative correlation between SST and pain relief duration after denervation ( -0.33, 95% CI -0.53 to -0.09, p < 0.01).
SST is a viable measurement with which to guide needle placement during RF denervation for lumbar facet pain, and enhances pain relief outcomes.
感觉刺激阈值(SST)已被用作一种替代标志物,以确定用于射频(RF)去神经支配的神经分支;然而,SST作为一种预后标志物的有效性仍存在争议。
评估较低的SST值是否与关节突源性下腰痛的射频去神经支配更好的结果相关。
前瞻性队列研究。
67例接受下腰痛射频去神经支配的患者。
使用Spearman相关系数()分析诊断性内侧支阻滞(MBB)的疼痛缓解平均百分比与RF去神经支配手术结果之间的相关性,以及SST与RF去神经支配手术结果之间的相关性。进行Wilcoxon秩和检验,以评估RF去神经支配后疼痛缓解的程度和持续时间是否因SST水平(<0.5和≥0.5)或诊断性MBB的疼痛缓解(<80%和≥80%)而有所不同。
诊断性MBB后的疼痛缓解与去神经支配后2周的疼痛缓解之间存在正相关(0.31,95%CI 0.08至0.51,p<0.01),但MBB后的疼痛缓解与去神经支配后6个月的疼痛缓解之间无相关性,去神经支配后的疼痛缓解持续时间也无相关性。SST与去神经支配后6个月的疼痛缓解之间存在负相关(-0.41,95%CI -0.59至-0.18,p<0.001)。SST与去神经支配后的疼痛缓解持续时间之间也存在负相关(-0.33,95%CI -0.53至-0.09,p<0.01)。
SST是一种可行的测量方法,可用于在腰椎小关节疼痛的RF去神经支配过程中指导针的放置,并提高疼痛缓解效果。